Literature DB >> 15462789

Liposomes as drug carriers in leishmaniasis and malaria.

C R Alving1.   

Abstract

Experimental studies suggest that liposomes could substantially improve the performance of anti-leishmanial drugs in the chemotherapy of visceral leishmaniasis. In this article, Carl Alving discusses the potential for overcoming resistance to antimonial drugs; for 'buffering' the toxicity of drugs, and for drug delivery under conditions where hospitalization is impossible or inconvenient. Liposomes can also be used experimentally to reduce the toxicity and increase the efficacy of parenterally-administered primaquine in the treatment of sporozoite-induced murine malaria.

Entities:  

Year:  1986        PMID： 15462789     DOI： 10.1016/0169-4758(86)90039-6

Source DB:  PubMed          Journal:  Parasitol Today        ISSN： 0169-4758


  9 in total

1.  Reduced tissue parasitic load and infectivity to sand flies in dogs naturally infected by Leishmania (Leishmania) chagasi following treatment with a liposome formulation of meglumine antimoniate.

Authors:  Raul R Ribeiro; Eliane P Moura; Vitor M Pimentel; Weverton M Sampaio; Sydnei M Silva; Dante A Schettini; Cintia F Alves; Ferdinan A Melo; Wagner L Tafuri; Cynthia Demicheli; Maria N Melo; Frédéric Frézard; Marilene S M Michalick
Journal:  Antimicrob Agents Chemother       Date:  2008-05-05       Impact factor: 5.191

Review 2.  Nanomedicines in gastroenterology and hepatology.

Authors:  Alf Lamprecht
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2015-03-10       Impact factor: 46.802

3.  Effect of nanoparticles on the therapeutic efficacy of praziquantel against Schistosoma mansoni infection in murine models.

Authors:  Alaa Eldin M Labib El Gendy; Faten Alsayed Mohammed; Sara A Abdel-Rahman; Thanaa Ibrahim Ahmed Shalaby; Ghada M Fathy; Samira Metwally Mohammad; Mahmoud A El-Shafey; Nesma Atef Mohammed
Journal:  J Parasit Dis       Date:  2019-04-03

4.  Scavenger receptor-mediated delivery of antisense mini-exon phosphorothioate oligonucleotide to Leishmania-infected macrophages. Selective and efficient elimination of the parasite.

Authors:  G Chaudhuri
Journal:  Biochem Pharmacol       Date:  1997-02-07       Impact factor: 5.858

5.  Efficacy of combined therapy with liposome-encapsulated meglumine antimoniate and allopurinol in treatment of canine visceral leishmaniasis.

Authors:  Sydnei M da Silva; Izabela F G Amorim; Raul R Ribeiro; Erly G Azevedo; Cynthia Demicheli; Maria N Melo; Wagner L Tafuri; Nelder F Gontijo; Marilene S M Michalick; Frédéric Frézard
Journal:  Antimicrob Agents Chemother       Date:  2012-03-12       Impact factor: 5.191

6.  Tuftsin-bearing liposomes as rifampin vehicles in treatment of tuberculosis in mice.

Authors:  A Agarwal; H Kandpal; H P Gupta; N B Singh; C M Gupta
Journal:  Antimicrob Agents Chemother       Date:  1994-03       Impact factor: 5.191

7.  Immunomodulation by liposome entrapped allergen.

Authors:  N Arora; S V Gangal
Journal:  Mol Cell Biochem       Date:  1990-09-21       Impact factor: 3.396

Review 8.  Nano-biotechnology: a new approach to treat and prevent malaria.

Authors:  Khaista Rahman; Shahid Ullah Khan; Shah Fahad; Ming Xian Chang; Aqleem Abbas; Wasim Ullah Khan; Lutfur Rahman; Zaheer Ul Haq; Ghulam Nabi; Dilfaraz Khan
Journal:  Int J Nanomedicine       Date:  2019-02-21

9.  Novel S-adenosyl-L-methionine decarboxylase inhibitors as potent antiproliferative agents against intraerythrocytic Plasmodium falciparum parasites.

Authors:  Dina le Roux; Pieter B Burger; Jandeli Niemand; Anne Grobler; Patricia Urbán; Xavier Fernàndez-Busquets; Robert H Barker; Adelfa E Serrano; Abraham I Louw; Lyn-Marie Birkholtz
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2013-12-05       Impact factor: 4.077
  9 in total

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