Literature DB >> 15461705

Inflammatory cytokines in acute renal failure.

Ganesan Ramesh1, W Brian Reeves.   

Abstract

A growing body of evidence indicates that inflammatory mechanisms contribute to toxin-induced acute renal failure as well as ischemia/reperfusion injury. A role for tumor necrosis factor-alpha (TNF-alpha) in mediating the inflammatory injury in cisplatin-induced acute renal failure has recently been established. Cisplatin induces the expression of TNF-alpha and TNF receptor subtype 2 (TNFR2) within the kidney. Genetic deletion of either TNF-alpha or TNFR2 substantially reduces cisplatin-induced renal failure and also necrosis and apoptosis within the kidney. Studies will be required to determine if pharmacologic inhibition of TNF-alpha might reduce cisplatin-induced renal failure in humans.

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Year:  2004        PMID： 15461705     DOI： 10.1111/j.1523-1755.2004.09109.x

Source DB:  PubMed          Journal:  Kidney Int Suppl        ISSN： 0098-6577            Impact factor:   10.545


  72 in total

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2.  Poly(ADP-ribose) polymerase-1 is a key mediator of cisplatin-induced kidney inflammation and injury.

Authors:  Partha Mukhopadhyay; Béla Horváth; Malek Kechrid; Galin Tanchian; Mohanraj Rajesh; Amarjit S Naura; A Hamid Boulares; Pál Pacher
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Authors:  Navjotsingh Pabla; Alice A Gibson; Mike Buege; Su Sien Ong; Lie Li; Shuiying Hu; Guoqing Du; Jason A Sprowl; Aksana Vasilyeva; Laura J Janke; Eberhard Schlatter; Taosheng Chen; Giuliano Ciarimboli; Alex Sparreboom
Journal:  Proc Natl Acad Sci U S A       Date:  2015-04-06       Impact factor: 11.205

4.  Loss of the Na+/H+ Exchange Regulatory Factor 1 Increases Susceptibility to Cisplatin-Induced Acute Kidney Injury.

Authors:  Adrienne Bushau-Sprinkle; Michelle Barati; Caryl Conklin; Tess Dupre; Kenneth B Gagnon; Syed J Khundmiri; Barbara Clark; Leah Siskind; Mark A Doll; Madhavi Rane; Michael Brier; Susan Coventry; Eleanor D Lederer
Journal:  Am J Pathol       Date:  2019-03-27       Impact factor: 4.307

Review 5.  Developing better mouse models to study cisplatin-induced kidney injury.

Authors:  Cierra N Sharp; Leah J Siskind
Journal:  Am J Physiol Renal Physiol       Date:  2017-07-19

6.  Modulation of angiotensin II-induced inflammatory cytokines by the Epac1-Rap1A-NHE3 pathway: implications in renal tubular pathobiology.

Authors:  Ping Xie; Darukeshwara Joladarashi; Pradeep Dudeja; Lin Sun; Yashpal S Kanwar
Journal:  Am J Physiol Renal Physiol       Date:  2014-02-19

7.  Cellular repressor of E1A stimulated genes enhances endothelial monolayer integrity.

Authors:  Yan Duan; Shaowei Liu; Jie Tao; Yang You; Guitang Yang; Chenghui Yan; Yaling Han
Journal:  Mol Biol Rep       Date:  2013-04-12       Impact factor: 2.316

8.  Malnutrition and inflammation in acute kidney injury due to earthquake-related crush syndrome.

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9.  Stress-responsive gene TauT and acute kidney injury.

Authors:  Xiaobin Han; Russell W Chesney
Journal:  J Biomed Sci       Date:  2010-08-24       Impact factor: 8.410

Review 10.  Toll-like receptors in kidney disease.

Authors:  Kelly D Smith
Journal:  Curr Opin Nephrol Hypertens       Date:  2009-05       Impact factor: 2.894
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