Literature DB >> 15459720

Maintaining integrity.

Yosef Shiloh1, Alan R Lehmann.   

Abstract

Research on genome stability and integrity now extends far beyond the biochemistry of DNA repair to encompass signal transduction pathways that span numerous aspects of cellular life. Derailed genomic integrity pathways can result in debilitating genetic disorders, premature ageing, predisposition to cancer and degenerative conditions. Current progress in this rapidly expanding field was the subject of an EMBO workshop, Maintenance of Genomic Integrity, that took place in June 2004 in Galway, Ireland. Top

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Year:  2004        PMID: 15459720     DOI: 10.1038/ncb1004-923

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN: 1465-7392            Impact factor:   28.824


  18 in total

Review 1.  Imaging of protein movement induced by chromosomal breakage: tiny 'local' lesions pose great 'global' challenges.

Authors:  Claudia Lukas; Jiri Bartek; Jiri Lukas
Journal:  Chromosoma       Date:  2005-06-30       Impact factor: 4.316

2.  The linear no-threshold relationship is inconsistent with radiation biologic and experimental data.

Authors:  Maurice Tubiana; Ludwig E Feinendegen; Chichuan Yang; Joseph M Kaminski
Journal:  Radiology       Date:  2009-04       Impact factor: 11.105

3.  A role for homologous recombination proteins in cell cycle regulation.

Authors:  Kaja Kostyrko; Sandra Bosshard; Zuzanna Urban; Nicolas Mermod
Journal:  Cell Cycle       Date:  2015-06-30       Impact factor: 4.534

Review 4.  Quality control of homologous recombination.

Authors:  Ting Liu; Jun Huang
Journal:  Cell Mol Life Sci       Date:  2014-05-25       Impact factor: 9.261

5.  Fumarase is involved in DNA double-strand break resection through a functional interaction with Sae2.

Authors:  Michael Leshets; Dharanidharan Ramamurthy; Michael Lisby; Norbert Lehming; Ophry Pines
Journal:  Curr Genet       Date:  2017-12-04       Impact factor: 3.886

6.  Mice lacking protein phosphatase 5 are defective in ataxia telangiectasia mutated (ATM)-mediated cell cycle arrest.

Authors:  Weidong Yong; Shideng Bao; Hanying Chen; Dapei Li; Edwin R Sánchez; Weinian Shou
Journal:  J Biol Chem       Date:  2007-03-21       Impact factor: 5.157

7.  Malfunctioning DNA damage response (DDR) leads to the degeneration of nigro-striatal pathway in mouse brain.

Authors:  Michal Kirshner; Ronit Galron; Dan Frenkel; Gil Mandelbaum; Yosef Shiloh; Zhao-Qi Wang; Ari Barzilai
Journal:  J Mol Neurosci       Date:  2011-09-16       Impact factor: 3.444

8.  A tissue graft model of DNA damage response in the normal and malignant human prostate.

Authors:  Taija M Af Hällström; Hongjuan Zhao; Junqiang Tian; Ville Rantanen; Stephen W Reese; Rosalie Nolley; Marikki Laiho; Donna M Peehl
Journal:  J Urol       Date:  2013-09-11       Impact factor: 7.450

9.  Opposing role of condensin and radiation-sensitive gene RAD52 in ribosomal DNA stability regulation.

Authors:  Chi Kwan Tsang; X F Steven Zheng
Journal:  J Biol Chem       Date:  2009-06-11       Impact factor: 5.157

10.  Tumor protein D52 represents a negative regulator of ATM protein levels.

Authors:  Yuyan Chen; Alvin Kamili; Jayne R Hardy; Guy E Groblewski; Kum Kum Khanna; Jennifer A Byrne
Journal:  Cell Cycle       Date:  2013-08-21       Impact factor: 4.534

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