| Literature DB >> 15459661 |
David R Hipfner1, Stephen M Cohen.
Abstract
Cells grow and divide rapidly during embryonic and postnatal development. Net tissue growth reflects the balance between the addition of new cells and the elimination of existing cells by programmed cell death. Cells compete for growth and survival factors to ensure an appropriate balance between the addition and elimination of cells. Elaborate mechanisms ensure that cells do not evade these constraints, and thereby prevent uncontrolled proliferation.Mesh:
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Year: 2004 PMID: 15459661 DOI: 10.1038/nrm1491
Source DB: PubMed Journal: Nat Rev Mol Cell Biol ISSN: 1471-0072 Impact factor: 94.444