OBJECTIVE: To identify predictors of quality of life (QOL) among women diagnosed with gestational trophoblastic tumor (GTT) 5-10 years earlier. STUDY DESIGN: Utilizing a cross-sectional, descriptive design, 111 survivors completed a comprehensive QOL interview. RESULTS: Univariate analyses revealed that numerous psychosocial variables correlated highly with overall QOL. However, multivariate analysis indicated that the significant predictors of long-term QOL were cancer-specific distress, social support, spiritual well-being, reproductive concerns, gynecologic pain and sexual functioning. These 6 variables accounted for 77% of the variance in the overall QOL score. Post hoc analyses demonstrated that each of the predictors had unique effects on the QOL score. CONCLUSION: The variables identified in this model can guide future research and clinical care to reduce short- and long-term burdens associated with GTT.
OBJECTIVE: To identify predictors of quality of life (QOL) among women diagnosed with gestational trophoblastic tumor (GTT) 5-10 years earlier. STUDY DESIGN: Utilizing a cross-sectional, descriptive design, 111 survivors completed a comprehensive QOL interview. RESULTS: Univariate analyses revealed that numerous psychosocial variables correlated highly with overall QOL. However, multivariate analysis indicated that the significant predictors of long-term QOL were cancer-specific distress, social support, spiritual well-being, reproductive concerns, gynecologic pain and sexual functioning. These 6 variables accounted for 77% of the variance in the overall QOL score. Post hoc analyses demonstrated that each of the predictors had unique effects on the QOL score. CONCLUSION: The variables identified in this model can guide future research and clinical care to reduce short- and long-term burdens associated with GTT.
Authors: Lari Wenzel; Aysun Dogan-Ates; Rana Habbal; Ross Berkowitz; Donald P Goldstein; Marilyn Bernstein; Brenda Coffey Kluhsman; Kathryn Osann; Edward Newlands; Michael J Seckl; Barry Hancock; David Cella Journal: J Natl Cancer Inst Monogr Date: 2005
Authors: Victoria Champion; Stephen D Williams; Anna Miller; Kristina M Reuille; Kim Wagler-Ziner; Patrick O Monahan; Qianqian Zhao; David Gershenson; David Cella Journal: Gynecol Oncol Date: 2007-03-13 Impact factor: 5.482
Authors: Valentina E Di Mattei; Letizia Carnelli; Martina Mazzetti; Martina Bernardi; Rossella Di Pierro; Alice Bergamini; Giorgia Mangili; Massimo Candiani; Lucio Sarno Journal: PLoS One Date: 2016-04-21 Impact factor: 3.240
Authors: Valentina E Di Mattei; Gaia Perego; Paola Taranto; Martina Mazzetti; Paola M V Rancoita; Francesca Milano; Giorgia Mangili; Emanuela Rabaiotti; Alice Bergamini; Raffaella Cioffi; Massimo Candiani Journal: Support Care Cancer Date: 2022-05-24 Impact factor: 3.359