Literature DB >> 15455155

Effect of chain length on transfection properties of spermine-based gemini surfactants.

Mariano Castro1, Derek Griffiths, Alpesh Patel, Nicola Pattrick, Chris Kitson, Mark Ladlow.   

Abstract

The synthesis and associated structure-activity relationships for gene transfection of a series of spermine-derived cationic gemini surfactants incorporating diamino acid headgroups and either identical (symmetrical) or different (unsymmetrical) lipophilic tailgroups is described. Transfection activity is found to depend critically upon the structural elements present. Copyright 2004 The Royal Society of Chemistry

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Year:  2004        PMID： 15455155     DOI： 10.1039/B410240A

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  4 in total

Review 1.  Transfection by cationic gemini lipids and surfactants.

Authors:  M Damen; A J J Groenen; S F M van Dongen; R J M Nolte; B J Scholte; M C Feiters
Journal:  Medchemcomm       Date:  2018-07-17       Impact factor: 3.597

2.  Transgene expression and effective gene silencing in vagal afferent neurons in vivo using recombinant adeno-associated virus vectors.

Authors:  M Kollarik; M J Carr; F Ru; C J A Ring; V J Hart; P Murdock; A C Myers; Y Muroi; B J Undem
Journal:  J Physiol       Date:  2010-08-24       Impact factor: 5.182

3.  The effect of polar headgroups and spacer length on the DNA transfection of cholesterol-based cationic lipids.

Authors:  Widchaya Radchatawedchakoon; Chopaka Thongbamrer; Wuttiphong Konbamrung; Phakamas Khattawee; Uthai Sakee; Wanlapa Roobsoong; Jetsumon Sattabongkot; Praneet Opanasopit; Boon-Ek Yingyongnarongkul
Journal:  RSC Med Chem       Date:  2020-01-06

Review 4.  Cationic Surfactants: Self-Assembly, Structure-Activity Correlation and Their Biological Applications.

Authors:  Lucia Ya Zakharova; Tatiana N Pashirova; Slavomira Doktorovova; Ana R Fernandes; Elena Sanchez-Lopez; Amélia M Silva; Selma B Souto; Eliana B Souto
Journal:  Int J Mol Sci       Date:  2019-11-06       Impact factor: 5.923
  4 in total

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