| Literature DB >> 15454238 |
Claire Mazier1, Maryse Jaouen, Marie-Agnès Sari, Didier Buisson.
Abstract
The oxidation of tert-butyl-phenyl group of title compounds by some microorganisms was studied. We have optimized the conditions of culture to increase the formation of acid metabolites and to avoid the formation of side products. We showed that an oxidative activity is induced by soybean peptones in Streptomyces platensis. The biologically active compounds, fexofenadine and carebastine, are produced in good yield (86-95%) by Absidia corymbifera.Entities:
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Year: 2004 PMID： 15454238 DOI： 10.1016/j.bmcl.2004.07.076
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823