| Literature DB >> 15454076 |
Sander M Houten1, Johan Auwerx.
Abstract
PGC-1alpha plays essential and diverse functions in the control of metabolism ranging from mitochondrial biogenesis and respiration to hepatic gluconeogenesis and muscle fiber-type switching. In a paper in this issue of Cell, the characterization of PGC-1alpha(-/-) mice illustrates these pleiotropic functions and reveals an unexpected role for PGC-1alpha in the brain.Entities:
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Year: 2004 PMID： 15454076 DOI： 10.1016/j.cell.2004.09.016
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582