Literature DB >> 15453938

Increasing annual incidence of vestibular schwannoma and age at diagnosis.

Sven-Eric Stangerup1, Mirko Tos, Per Caye-Thomasen, Tina Tos, Mads Klokker, Jens Thomsen.   

Abstract

During the last 26 years the annual number of diagnosed vestibular schwannomas (VS) has been increasing. The aim of this study is to describe and analyse this increase. Since 1976, 1446 new cases of VS have been diagnosed at the authors' centre. Special focus was on the age at diagnosis, the localization and the size of the tumour. The size of the tumour was registered as either intrameatal or with the largest extrameatal diameter. The annual number of diagnosed VS has increased from 26 in 1976 to 101 in 2001. The size of the diagnosed tumours has decreased from a median of 35 mm in 1979 to 10 mm in 2001. In the first years large and giant tumours dominated, in contrast to recent years in which intrameatal and small tumours dominated. The median age at the time of diagnosis has been almost unchanged through the period (median 55 years). If the decreasing size of the tumour and the increasing incidence of VS can be explained only by earlier diagnosis and easier access to magnetic resonance (MR) scanning it should be expected that the median age at the time of diagnosis would decrease simultaneously. In this study, the median age at the time of diagnosis has been almost unchanged throughout the 26-year period. This paradox can be explained by the fact that, with easier access to MR scanning, the examination has been offered also to elderly patients, in whom the small and intrameatal tumours dominate.

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Year:  2004        PMID: 15453938     DOI: 10.1258/0022215041917989

Source DB:  PubMed          Journal:  J Laryngol Otol        ISSN: 0022-2151            Impact factor:   1.469


  18 in total

1.  Long-term hearing preservation after microsurgical excision of vestibular schwannoma.

Authors:  Erika Ann Woodson; Ryan Douglas Dempewolf; Samuel Paul Gubbels; Aaron Thomas Porter; Jacob Jay Oleson; Marlan Rex Hansen; Bruce Jay Gantz
Journal:  Otol Neurotol       Date:  2010-09       Impact factor: 2.311

2.  Main Symptom that Led to Medical Evaluation and Diagnosis of Vestibular Schwannoma and Patient-Reported Tumor Size: Cross-sectional Study in 1,304 Patients.

Authors:  Maria Peris-Celda; Christopher S Graffeo; Avital Perry; Panagiotis Kerezoudis; Nicole M Tombers; Matthew L Carlson; Michael J Link
Journal:  J Neurol Surg B Skull Base       Date:  2018-10-09

3.  Expectant management of vestibular schwannoma: a retrospective multivariate analysis of tumor growth and outcome.

Authors:  Mark Hughes; Christopher Skilbeck; Shakeel Saeed; Robert Bradford
Journal:  Skull Base       Date:  2011-09

Review 4.  Therapeutic advances for the tumors associated with neurofibromatosis type 1, type 2, and schwannomatosis.

Authors:  Jaishri O Blakeley; Scott R Plotkin
Journal:  Neuro Oncol       Date:  2016-02-06       Impact factor: 12.300

5.  Intralabyrinthine schwannomas: a new surgical treatment.

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Journal:  Eur Arch Otorhinolaryngol       Date:  2018-03-20       Impact factor: 2.503

Review 6.  [Quality of life in patients with vestibular schwannoma].

Authors:  I Baumann; P K Plinkert
Journal:  HNO       Date:  2017-09       Impact factor: 1.284

7.  Antiangiogenic agents for nonmalignant brain tumors.

Authors:  Ammar H Hawasli; Joshua B Rubin; David D Tran; Douglas R Adkins; Shahid Waheed; Timothy E Hullar; David H Gutmann; John Evans; Jeffrey R Leonard; Gregory J Zipfel; Michael R Chicoine
Journal:  J Neurol Surg B Skull Base       Date:  2013-03-13

8.  Does where you live influence how your vestibular schwannoma is managed? Examining geographical differences in vestibular schwannoma treatment across the United States.

Authors:  Matthew L Carlson; Amy E Glasgow; Brandon R Grossardt; Elizabeth B Habermann; Michael J Link
Journal:  J Neurooncol       Date:  2016-06-22       Impact factor: 4.130

Review 9.  Racial, ethnic and socioeconomic disparities in the treatment of brain tumors.

Authors:  William T Curry; Fred G Barker
Journal:  J Neurooncol       Date:  2009-05-09       Impact factor: 4.130

10.  Outcome after translabyrinthine surgery for vestibular schwannomas: report on 1244 patients.

Authors:  Jacob Bertram Springborg; Kåre Fugleholm; Lars Poulsgaard; Per Cayé-Thomasen; Jens Thomsen; Sven-Eric Stangerup
Journal:  J Neurol Surg B Skull Base       Date:  2012-06
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