Literature DB >> 15453742

Alkenes from terminal epoxides using lithium 2,2,6,6-tetramethylpiperidide and organolithiums or grignard reagents.

David M Hodgson1, Matthew J Fleming, Steven J Stanway.   

Abstract

E-Alkenes (including arylated alkenes, dienes, and allylsilanes) are efficiently prepared by alpha-deprotonation of terminal epoxides using lithium 2,2,6,6-tetramethylpiperidide, followed by in situ trapping with organolithiums or Grignard reagents.

Entities:  

Year:  2004        PMID: 15453742     DOI: 10.1021/ja045513a

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  2 in total

Review 1.  Ring opening of epoxides with C-nucleophiles.

Authors:  Sadia Faiz; Ameer Fawad Zahoor
Journal:  Mol Divers       Date:  2016-07-04       Impact factor: 2.943

2.  Total Synthesis of Resveratrone and iso-Resveratrone.

Authors:  Stefan Fritsch; Nazli Aldemir; Jan Balszuweit; Kevin Bojaryn; Jens Voskuhl; Christoph Hirschhäuser
Journal:  ChemistryOpen       Date:  2022-06-30       Impact factor: 2.630

  2 in total

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