Literature DB >> 15452976

Tissue-specific and differential expression of prothymosin alpha gene during rat development.

M Dosil1, M Freire, J Gómez-Márquez.   

Abstract

We have analyzed the RNA expression of prothymosin alpha (ProT alpha) gene during rat development in several tissues and compared it to that of two proteins related to cell proliferation: proliferating cell nuclear antigen (PCNA)/cyclin and histone H3 (H3). The expression of ProT alpha gene was found to be regulated in a developmental and tissue-specific manner. The mRNA levels of ProT alpha followed a similar time-course in liver, brain, kidney, and testis, being highly increased in the early periods of postnatal development. However, in thymus ProT alpha mRNA showed only moderate changes throughout development. Our findings suggest that ProT alpha participates in developmental processes like cell proliferation and/or differentiation.

Entities:  

Mesh：

Substances：

Year:  1990        PMID： 15452976     DOI： 10.1016/0014-5793(90)81196-u

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  6 in total

1.  Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses.

Authors:  Wayne Chadwick; Yu Zhou; Sung-Soo Park; Liyun Wang; Nicholas Mitchell; Matthew D Stone; Kevin G Becker; Bronwen Martin; Stuart Maudsley
Journal:  PLoS One       Date:  2010-12-17       Impact factor: 3.240

2.  Identification of estrogen-responsive genes in neuroblastoma SK-ER3 cells.

Authors:  M Garnier; D Di Lorenzo; A Albertini; A Maggi
Journal:  J Neurosci       Date:  1997-06-15       Impact factor: 6.167

3.  Expression of alpha-thymosins in human tissues in normal and abnormal growth.

Authors:  O E Tsitsiloni; J Stiakakis; A Koutselinis; J Gogas; C Markopoulos; P Yialouris; S Bekris; D Panoussopoulos; V Kiortsis; W Voelter
Journal:  Proc Natl Acad Sci U S A       Date:  1993-10-15       Impact factor: 11.205

4.  Immunohistochemical location of prothymosin alpha in regenerating human hepatocytes and hepatocellular carcinomas.

Authors:  M Fraga; T García-Caballero; F Domínguez; E Pérez-Becerra; A Beiras; J Forteza
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1993

5.  Age- and sex-related differences in the content of prothymosin alpha in rat tissues.

Authors:  S Frillingos; O Tsolas
Journal:  Experientia       Date:  1992-03-15

6.  Subcellular dissemination of prothymosin alpha at normal physiology: immunohistochemical vis-a-vis western blotting perspective.

Authors:  Caroline Mwendwa Kijogi; Christopher Khayeka-Wandabwa; Keita Sasaki; Yoshimasa Tanaka; Hiroshi Kurosu; Hayato Matsunaga; Hiroshi Ueda
Journal:  BMC Physiol       Date:  2016-03-01
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.