Literature DB >> 15452305

Association of an ABCB1 gene haplotype with pharmacoresistance in temporal lobe epilepsy.

F Zimprich1, R Sunder-Plassmann, E Stogmann, A Gleiss, A Dal-Bianco, A Zimprich, S Plumer, C Baumgartner, C Mannhalter.   

Abstract

The multidrug transporter P-glycoprotein is suspected of contributing to pharmacoresistance in temporal lobe epilepsy (TLE). To assess the role of functional variations in its coding gene (ABCB1) the authors genotyped 210 patients with TLE who were stratified according to their degree of drug resistance. They identified a common haplotype that when present in the homozygous state significantly increased the risk for pharmacoresistance.

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Year:  2004        PMID： 15452305     DOI： 10.1212/01.wnl.0000141021.42763.f6

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  29 in total

1.  Association between ABCB1-T1236C polymorphism and drug-resistant epilepsy in Iranian female patients.

Authors:  Mehri Maleki; Mohammad Sayyah; Fatemeh Kamgarpour; Morteza Karimipoor; Aida Arab; Anahita Rajabi; Kourosh Gharagozli; Ahmad Reza Shamshiri; Esmaeil Shahsavand Ananloo
Journal:  Iran Biomed J       Date:  2010-07

2.  Biomarkers for antiepileptic drug response.

Authors:  Tracy A Glauser
Journal:  Biomark Med       Date:  2011-10       Impact factor: 2.851

3.  Refractory epilepsy: one size does not fit all.

Authors:  Jacqueline A French
Journal:  Epilepsy Curr       Date:  2006 Nov-Dec       Impact factor: 7.500

4.  Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein).

Authors:  Laura M Hodges; Svetlana M Markova; Leslie W Chinn; Jason M Gow; Deanna L Kroetz; Teri E Klein; Russ B Altman
Journal:  Pharmacogenet Genomics       Date:  2011-03       Impact factor: 2.089

5.  Combined effects of epileptic seizure and phenobarbital induced overexpression of P-glycoprotein in brain of chemically kindled rats.

Authors:  Xinyue Jing; Xiang Liu; Tao Wen; Shanshan Xie; Dan Yao; Xiaodong Liu; Guangji Wang; Lin Xie
Journal:  Br J Pharmacol       Date:  2010-03-03       Impact factor: 8.739

6.  Multimodal imaging of language reorganization in patients with left temporal lobe epilepsy.

Authors:  Yu-Hsuan A Chang; Nobuko Kemmotsu; Kelly M Leyden; N Erkut Kucukboyaci; Vicente J Iragui; Evelyn S Tecoma; Leena Kansal; Marc A Norman; Rachelle Compton; Tobin J Ehrlich; Vedang S Uttarwar; Anny Reyes; Brianna M Paul; Carrie R McDonald
Journal:  Brain Lang       Date:  2017-04-20       Impact factor: 2.381

7.  Association of MDR1 gene C3435T polymorphism with childhood intractable epilepsy: a meta-analysis.

Authors:  Guilian Sun; Xue Sun; Limei Guan
Journal:  J Neural Transm (Vienna)       Date:  2014-02-20       Impact factor: 3.575

8.  Role of multidrug transporters in neurotherapeutics.

Authors:  Manna Jose; Sanjeev V Thomas
Journal:  Ann Indian Acad Neurol       Date:  2009-04       Impact factor: 1.383

Review 9.  Imaging the function of P-glycoprotein with radiotracers: pharmacokinetics and in vivo applications.

Authors:  P Kannan; C John; S S Zoghbi; C Halldin; M M Gottesman; R B Innis; M D Hall
Journal:  Clin Pharmacol Ther       Date:  2009-07-22       Impact factor: 6.875

10.  ABCB1 gene polymorphisms and haplotype analysis in colorectal cancer.

Authors:  Mariusz Panczyk; Ewa Balcerczak; Sylwester Piaskowski; Krzysztof Jamroziak; Grazyna Pasz-Walczak; Marek Mirowski
Journal:  Int J Colorectal Dis       Date:  2009-05-05       Impact factor: 2.571
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