| Literature DB >> 15452262 |
Thomas Rowe1, Guangping Gao, Robert J Hogan, Ronald G Crystal, Thomas G Voss, Rebecca L Grant, Peter Bell, Gary P Kobinger, Nelson A Wivel, James M Wilson.
Abstract
Rhesus and cynomolgus macaques were challenged with 10(7) PFU of a clinical isolate of the severe acute respiratory syndrome (SARS) coronavirus. Some of the animals developed a mild self-limited respiratory infection very different from that observed in humans with SARS. The macaque model as it currently exists will have limited utility in the study of SARS and the evaluation of therapies.Entities:
Mesh:
Year: 2004 PMID: 15452262 PMCID: PMC521815 DOI: 10.1128/JVI.78.20.11401-11404.2004
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103