Biomechanics of metastatic spine cancer.

The spine is the most common site of skeletal metastases. Most of these occur within the vertebral body, thereby predisposing patients to pathologic fracture. The risk of fracture is related to the extent of bony destruction, location of the lesion, and inherent bone quality. The regional variation in spine anatomy exposes the cervical,thoracic, and lumbar spines to different forces,resulting in varying fracture types.