| Literature DB >> 1545026 |
C DeCarli1, J Maisog, D G Murphy, D Teichberg, S I Rapoport, B Horwitz.
Abstract
We describe a simple, rapid, and semiautomated method of MR analysis based on mathematical modeling of MR pixel intensity histograms. The method is shown to be accurate and reliable for regional analysis of brain, central, and subarachnoid CSF volumes. Application of the method to five young and six older subjects revealed significant age-related changes in regional brain volumes whereas no difference was found for traced central CSF volumes or subarachnoid CSF volumes. We conclude that this is a simple method that can be applied to further studies of quantification of brain structure in healthy aging and brain disease.Entities:
Mesh:
Year: 1992 PMID: 1545026 DOI: 10.1097/00004728-199203000-00018
Source DB: PubMed Journal: J Comput Assist Tomogr ISSN: 0363-8715 Impact factor: 1.826