Literature DB >> 15448390

Management of septic arthritis.

Avinash K Shetty1, Abraham Gedalia.   

Abstract

Septic arthritis in children remains a serious disease with the potential for significant systemic and musculoskeletal morbidity. Staphlococcus aureus is the most common cause of bone and joint infections in all age groups. Microbial invasion of the synovial space occurs typically results from hematogenous seeding. Diagnosis in neonates and young infants can be difficult since the clinical signs are much less specific in these age groups. Early diagnosis by needle aspiration of the affected joint and prompt initiation of appropriate antimicrobial therapy in conjunction with drainage of the affected joint is critical to avoid destruction of the articular cartilage and prevent disability. Septic arthritis in infants and children should always be managed by a pediatrician in close consultation with an orthopedic surgeon. Empiric antibiotic regimens should always include adequate anti-staphylococcal coverage. Antibiotic treatment should be started with appropriate doses of intravenous antibiotics. Switch to oral antibiotic therapy can be made when patient demonstrates clinical improvement. A minimum of 3-4 weeks of therapy is recommended. Close follow-up is warranted to monitor the growth of the affected limb until skeletal maturity.

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Year:  2004        PMID: 15448390     DOI: 10.1007/bf02730722

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN: 0019-5456            Impact factor:   1.967


  20 in total

Review 1.  Imaging in the diagnosis of musculoskeletal infections in children.

Authors:  G A Mandell
Journal:  Curr Probl Pediatr       Date:  1996-08

2.  Serum C-reactive protein, erythrocyte sedimentation rate and white blood cell count in septic arthritis of children.

Authors:  M J Kallio; L Unkila-Kallio; K Aalto; H Peltola
Journal:  Pediatr Infect Dis J       Date:  1997-04       Impact factor: 2.129

Review 3.  Management of acute hematogenous osteomyelitis and septic arthritis in the pediatric patient.

Authors:  R Dagan
Journal:  Pediatr Infect Dis J       Date:  1993-01       Impact factor: 2.129

Review 4.  Synovial fluid analysis. A critical reappraisal.

Authors:  R H Shmerling
Journal:  Rheum Dis Clin North Am       Date:  1994-05       Impact factor: 2.670

Review 5.  Osteomyelitis and septic arthritis in children: appropriate use of imaging to guide treatment.

Authors:  D Jaramillo; S T Treves; J R Kasser; M Harper; R Sundel; T Laor
Journal:  AJR Am J Roentgenol       Date:  1995-08       Impact factor: 3.959

6.  Clindamycin treatment of invasive infections caused by community-acquired, methicillin-resistant and methicillin-susceptible Staphylococcus aureus in children.

Authors:  Gerardo Martínez-Aguilar; Wendy A Hammerman; Edward O Mason; Sheldon L Kaplan
Journal:  Pediatr Infect Dis J       Date:  2003-07       Impact factor: 2.129

7.  Pyogenic arthritis in infants and children: a review of 95 cases.

Authors:  C J Welkon; S S Long; M C Fisher; P D Alburger
Journal:  Pediatr Infect Dis       Date:  1986 Nov-Dec

8.  Oral antibiotic therapy of skeletal infections in children.

Authors:  E Kolyvas; G Ahronheim; M I Marks; R Gledhill; H Owen; L Rosenthall
Journal:  Pediatrics       Date:  1980-05       Impact factor: 7.124

9.  Experimental models of bacterial arthritis: a microbiologic and histopathologic characterization of the arthritis after the intraarticular injections of Neisseria gonorrhoeae, Staphylococcus aureus, group A streptococci, and Escherichia coli.

Authors:  D L Goldenberg; P L Chisholm; P A Rice
Journal:  J Rheumatol       Date:  1983-02       Impact factor: 4.666

Review 10.  Clinical and molecular aspects of the pathogenesis of Staphylococcus aureus bone and joint infections.

Authors:  R Cunningham; A Cockayne; H Humphreys
Journal:  J Med Microbiol       Date:  1996-03       Impact factor: 2.472

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  1 in total

1.  Septic arthritis in a Nigerian tertiary hospital.

Authors:  Johnson D Ogunlusi; Olugbemisola O Ogunlusi; Lawrence M Oginni; Julius A Olowookere
Journal:  Iowa Orthop J       Date:  2006
  1 in total

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