| Literature DB >> 15447515 |
Abstract
We build upon our previous analytical results for the Penna model of senescence to include positive mutations. We investigate whether a small but nonzero positive mutation rate gives qualitatively different results to the traditional Penna model in which no positive mutations are considered. We find that the high-lifespan tail of the distribution is radically changed in structure, but that there is not much effect on the bulk of the population. The mortality plateau that we found previously for a stochastic generalization of the Penna model is stable to a small positive mutation rate.Mesh:
Year: 2004 PMID: 15447515 DOI: 10.1103/PhysRevE.70.021907
Source DB: PubMed Journal: Phys Rev E Stat Nonlin Soft Matter Phys ISSN: 1539-3755