Literature DB >> 1544691

Erythrocyte nucleotides in lead workers.

M Ichiba1, K Tomokuni, K Mori.   

Abstract

We determined erythrocyte nucleotides levels in 22 lead workers with blood lead ranging from 8 to 78 micrograms/dl. Their erythrocyte pyrimidine 5'-nucleotidase (P5N) activity ranged from 19.4 to 3.4 mumol uridine/h per g hemoglobin. A significant elevation of erythrocyte pyrimidine nucleotides was found, and their contents correlated inversely with erythrocyte P5N activity and positively with blood lead concentration. In particular, the contents of uridine triphosphate (UTP) and cytidine triphosphate (CTP) exhibited a high correlation with P5N activity (r = -0.56, -0.54). However, its concentration in lead workers was estimated to be much lower than that in hereditary P5N deficiency.

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Year:  1992        PMID： 1544691     DOI： 10.1007/bf00386938

Source DB:  PubMed          Journal:  Int Arch Occup Environ Health        ISSN： 0340-0131            Impact factor:   3.015


  19 in total

1.  Effects of low-level lead exposure on pyrimidine 5'-nucleotidase and other erythrocyte enzymes. Possible role of pyrimidine 5'-nucleotidase in the pathogenesis of lead-induced anemia.

Authors:  D E Paglia; W N Valentine; J G Dahlgren
Journal:  J Clin Invest       Date:  1975-11       Impact factor: 14.808

2.  Erythrocyte pyrimidine 5'-nucleotidase test for occupational lead exposure.

Authors:  M Ichiba; K Tomokuni; K Sugimoto
Journal:  Ind Health       Date:  1987       Impact factor: 2.179

3.  Simple determination of erythrocyte pyrimidine 5'-nucleotidase activity in human blood by high-performance liquid chromatography.

Authors:  K Tomokuni; M Ichiba
Journal:  Ind Health       Date:  1986       Impact factor: 2.179

4.  Red cell pyrimidine 5' nucleotidase deficiency: determination of nucleotidase activity and nucleotide content using HPLC.

Authors:  C G Adair; G E Elder; T R Lappin; J M Bridges; M G Nelson
Journal:  Clin Chim Acta       Date:  1988-01-15       Impact factor: 3.786

5.  Erythrocyte nucleotide pattern in two children in a Norwegian family with pyrimidine 5'-nucleotidase deficiency.

Authors:  A Ericson; C H de Verdier; T W Hansen; M Seip
Journal:  Clin Chim Acta       Date:  1983-10-31       Impact factor: 3.786

6.  Lead-induced accumulation of erythrocyte pyrimidine nucleotides in the rabbit.

Authors:  C R Angle; S J Stohs; M S McIntire; M S Swanson; K S Rovang
Journal:  Toxicol Appl Pharmacol       Date:  1980-06-15       Impact factor: 4.219

7.  Red-cell pyrimidine 5'-nucleotidase and lead poisoning.

Authors:  H A Buc; J C Kaplan
Journal:  Clin Chim Acta       Date:  1978-07-01       Impact factor: 3.786

8.  Lead poisoning. Further observations on erythrocyte pyrimidine-nucleotidase deficiency and intracellular accumulation of pyrimidine nucleotides.

Authors:  D E Paglia; W N Valentine; K Fink
Journal:  J Clin Invest       Date:  1977-12       Impact factor: 14.808

9.  Erythrocyte nucleotides in children--increased blood lead and cytidine triphosphate.

Authors:  C R Angle; M S McIntire; M S Swanson; S J Stohs
Journal:  Pediatr Res       Date:  1982-04       Impact factor: 3.756

10.  Studies on erythrocyte pyrimidine 5'-nucleotidase (P5N) test and its evaluation in workers occupationally exposed to lead.

Authors:  M Ichiba; K Tomokuni
Journal:  Int Arch Occup Environ Health       Date:  1990       Impact factor: 3.015
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  1 in total

1.  Oral Administration of Ganoderma lucidum to Lead-Exposed Rats Protects Erythrocytes against Hemolysis: Implicates to Anti-Anemia.

Authors:  Shahdat Hossain; Sujan Bhowmick; Saiful Islam; Liza Rozario; Sabrin Jahan; Mehedi Hassan; Marzan Sarkar; Bazlul Karim Choudhury; Sohel Ahmed; Hussain Shahjalal
Journal:  Evid Based Complement Alternat Med       Date:  2015-08-02       Impact factor: 2.629
  1 in total

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