| Literature DB >> 154353 |
R A Jones, A R Buckpitt, H H Londer, C E Myers, B A Chabner, M R Boyd.
Abstract
A new high-pressure liquid chromatographic method for the clinical assay of 5-fluorouracil and 5-fluoroudexyuridine has been developed. The sensitivity and specificity of the method equals that of gas chromatography/mass spectrometric methods. The practical value of the method has been demonstrated by its application in several preliminary clinical studies of 5-fluorouracil in which plasma levels of 10(-8)-10(-6)M were readily monitored.Entities:
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Year: 1979 PMID： 154353
Source DB: PubMed Journal: Bull Cancer ISSN： 0007-4551 Impact factor: 1.276