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Literature DB >> 15422094

On the nature of the toxic component of the somatic antigen of Shigella paradysenteriae type Z (Flexner).

Abstract

From the chemical evidence presented it appears that the toxicity associated with the somatic antigen of Type Z Sh. paradysenteriae may be attributed to an entity distinct from the known components of the complex. That this substance is neither the protein, the lipid, nor the carbohydrate component of the antigen is evident. Because of its lability to chemical manipulation, the nature of the toxic component, has not yet been ascertained.

Entities: Chemical Disease Species

Keywords: ANTIGENS AND ANTIBODIES; DYSENTERY

Mesh：

Substances：
Antibodies
Antigens

Year: 1950 PMID： 15422094 PMCID： PMC2136025 DOI： 10.1084/jem.92.1.25

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

7 in total

1. Studies in immuno-chemistry: The isolation and properties of a specific antigenic substance from B. dysenteriae (Shiga).

Authors: W T Morgan
Journal: Biochem J Date: 1937-11 Impact factor: 3.857

2. Studies in immunochemistry: The fractionation and nature of antigenic material isolated from Bact. dysenteriae (Shiga).

Authors: W T Morgan; S M Partridge
Journal: Biochem J Date: 1940-02 Impact factor: 3.857

3. The estimation of phosphorus.

Authors: R J Allen
Journal: Biochem J Date: 1940-06 Impact factor: 3.857

4. Further studies of the immunological properties of polysaccharides from Serratia marcescens (Bacillus prodigiosus) the effects of passive and active immunization on the lethal activity of the polysaccharides.

Authors: H J CREECH; R F HANKWITZ; D R A WHARTON
Journal: Cancer Res Date: 1949-03 Impact factor: 12.701

5. STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : V. A QUANTITATIVE STUDY OF THE SEROLOGICAL CROSS-REACTIONS.

Authors: E Perlman; W F Goebel
Journal: J Exp Med Date: 1946-08-31 Impact factor: 14.307

6. STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : II. THE CHEMICAL DEGRADATION OF THE SPECIFIC ANTIGEN OF TYPE Z SHIGELLA PARADYSENTERIAE (FLEXNER).

Authors: F Binkley; W F Goebel; E Perlman
Journal: J Exp Med Date: 1945-04-01 Impact factor: 14.307

7. STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : I. THE SPECIFIC ANTIGENS OF SHIGELLA PARADYSENTERIAE (FLEXNER).

Authors: W F Goebel; F Binkley; E Perlman
Journal: J Exp Med Date: 1945-04-01 Impact factor: 14.307

7 in total

11 in total

1. EXPERIMENTAL SALMONELLOSIS. III. NEW TOXIC FRACTION (L) OBTAINED FROM SALMONELLA ENTERITIDIS AND ITS IMMUNOLOGICAL PROPERTIES.

Authors: M KAWAKAMI; N OSAWA; S MITSUHASHI
Journal: J Bacteriol Date: 1963-10 Impact factor: 3.490

On the nature of the toxic component of the somatic antigen of Shigella paradysenteriae type Z (Flexner).

1. Studies in immuno-chemistry: The isolation and properties of a specific antigenic substance from B. dysenteriae (Shiga).

2. Studies in immunochemistry: The fractionation and nature of antigenic material isolated from Bact. dysenteriae (Shiga).

3. The estimation of phosphorus.

4. Further studies of the immunological properties of polysaccharides from Serratia marcescens (Bacillus prodigiosus) the effects of passive and active immunization on the lethal activity of the polysaccharides.

5. STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : V. A QUANTITATIVE STUDY OF THE SEROLOGICAL CROSS-REACTIONS.

6. STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : II. THE CHEMICAL DEGRADATION OF THE SPECIFIC ANTIGEN OF TYPE Z SHIGELLA PARADYSENTERIAE (FLEXNER).

7. STUDIES ON THE FLEXNER GROUP OF DYSENTERY BACILLI : I. THE SPECIFIC ANTIGENS OF SHIGELLA PARADYSENTERIAE (FLEXNER).

1. EXPERIMENTAL SALMONELLOSIS. III. NEW TOXIC FRACTION (L) OBTAINED FROM SALMONELLA ENTERITIDIS AND ITS IMMUNOLOGICAL PROPERTIES.

2. Symposium on bacterial endotoxins. I. Relationship of chemical composition to biological activity.

Review 3. The effects of bacterial endotoxins on host mediation systems. A review.

Review 4. Molecular aspects of endotoxic reactions.

5. Immunochemical study of a bacterial endotoxin: Shigella flexneri type Z.

6. EXPERIMENTAL SALMONELLOSIS. IV. LIPID CONTENT OF TOXIN L OBTAINED FROM SALMONELLA ENTERITIDIS.

7. In vitro detoxification of bacterial endotoxin by macrophages.

8. Preparation and host-reactive properties of endotoxin with low content of nitrogen and lipid.

9. Lipopolysaccharide induces recurrence of arthritis in rat joints previously injured by peptidoglycan-polysaccharide.

10. Biological properties of parent endotoxins and lipoid fractions, with a kinetic study of acid-hydrolyzed endotoxin.