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Literature DB >> 15422092

Relation of virulence of pneumococcal strains for mice to the quantity of capsular polysaccharide formed in vitro.

Abstract

The amount of capsular polysaccharide formed in vitro by strains of pneumococcus types II, III, and VII of different virulence for mice has been measured by quantitative precipitin reactions. The quantity produced by strains of high virulence was greater for all three types than that formed by moderately virulent or avirulent strains. It is suggested that an important factor concerned in variations of virulence of pneumococci for mice is the genetic apparatus that controls the amount of SSS synthesized by the cells.

Entities: Chemical Disease Species

Keywords: PNEUMOCOCCI; POLYSACCHARIDES

Mesh：

Substances：

Year: 1950 PMID： 15422092 PMCID： PMC2136027 DOI： 10.1084/jem.92.1.1

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

4 in total

1. STEPWISE INTRATYPE TRANSFORMATION OF PNEUMOCOCCUS FROM R TO S BY WAY OF A VARIANT INTERMEDIATE IN CAPSULAR POLYSACCHARIDE PRODUCTION.

Authors: C M Macleod; M R Krauss
Journal: J Exp Med Date: 1947-11-30 Impact factor: 14.307

2. THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND HOMOLOGOUS ANTIBODY : III. A QUANTITATIVE STUDY AND A THEORY OF THE REACTION MECHANISM.

Authors: M Heidelberger; F E Kendall
Journal: J Exp Med Date: 1935-03-31 Impact factor: 14.307

3. Additive effects of certain transforming agents from some variants of pneumococcus.

Authors: H E TAYLOR
Journal: J Exp Med Date: 1949-04-01 Impact factor: 14.307

4. THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND HOMOLOGOUS ANTIBODY : II. CONDITIONS FOR QUANTITATIVE PRECIPITATION OF ANTIBODY IN HORSE SERA.

Authors: M Heidelberger; F E Kendall
Journal: J Exp Med Date: 1935-03-31 Impact factor: 14.307

4 in total

41 in total

1. Effect of intrastrain variation in the amount of capsular polysaccharide on genetic transformation of Streptococcus pneumoniae: implications for virulence studies of encapsulated strains.

Authors: J N Weiser; M Kapoor
Journal: Infect Immun Date: 1999-07 Impact factor: 3.441

2. The effect of some variables on experimental Klebsiella infections in mice.

Authors: S S EPSTEIN; P M PAYNE
Journal: J Hyg (Lond) Date: 1959-03

3. The pathogenicity of Klebsiella pneumoniae for mice: the relationship to the quantity and rate of production of type-specific capsular polysaccharide.

Authors: H BAER; L EHRENWORTH
Journal: J Bacteriol Date: 1956-11 Impact factor: 3.490

10. Position of O-Acetylation within the Capsular Repeat Unit Impacts the Biological Properties of Pneumococcal Serotypes 33A and 33F.

Authors: Brady L Spencer; Jamil S Saad; Anukul T Shenoy; Carlos J Orihuela; Moon H Nahm
Journal: Infect Immun Date: 2017-06-20 Impact factor: 3.441

Relation of virulence of pneumococcal strains for mice to the quantity of capsular polysaccharide formed in vitro.

1. STEPWISE INTRATYPE TRANSFORMATION OF PNEUMOCOCCUS FROM R TO S BY WAY OF A VARIANT INTERMEDIATE IN CAPSULAR POLYSACCHARIDE PRODUCTION.

2. THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND HOMOLOGOUS ANTIBODY : III. A QUANTITATIVE STUDY AND A THEORY OF THE REACTION MECHANISM.

3. Additive effects of certain transforming agents from some variants of pneumococcus.

4. THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND HOMOLOGOUS ANTIBODY : II. CONDITIONS FOR QUANTITATIVE PRECIPITATION OF ANTIBODY IN HORSE SERA.

1. Effect of intrastrain variation in the amount of capsular polysaccharide on genetic transformation of Streptococcus pneumoniae: implications for virulence studies of encapsulated strains.

2. The effect of some variables on experimental Klebsiella infections in mice.

3. The pathogenicity of Klebsiella pneumoniae for mice: the relationship to the quantity and rate of production of type-specific capsular polysaccharide.

4. Preparation of polynucleotide complex from Salmonella typhosa 1,2.

5. Streptococcus pneumoniae Elaborates Persistent and Prolonged Competent State during Pneumonia-Derived Sepsis.

6. Strong association between capsular type and virulence for mice among human isolates of Streptococcus pneumoniae.

7. Lobar pneumonia in rats produced by clinical isolates of Klebsiella pneumoniae.

8. Type-specific capsular antigen is associated with virulence in late-onset group B Streptococcal type III disease.

9. Production and characterization of monoclonal antibodies specific for Shewanella colwelliana exopolysaccharide.

10. Position of O-Acetylation within the Capsular Repeat Unit Impacts the Biological Properties of Pneumococcal Serotypes 33A and 33F.