| Literature DB >> 15415508 |
B BLACK-SCHAFFER, J W MILAM, D D BROCKMAN, E V COONRAD, S B SILVERMAN.
Abstract
In the hypersensitive animal a single inoculation of homologous antigen mixed with Shwartzman preparatory toxin may lead to the production of a Shwartzman reaction which functions as an amplifier of the antigen-antibody tissue response. The combination of antigen and bacterial toxin does not alter the antigenicity of purified bovine gamma globulin. This form of the Shwartzman phenomenon may be useful in the investigation of hyperergic tissue reactions.Entities:
Keywords: SHWARTZMAN PHENOMENON
Mesh:
Substances:
Year: 1950 PMID: 15415508 PMCID: PMC2135984 DOI: 10.1084/jem.91.5.539
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307