Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Generation of human monoclonal antibodies that confer protection against pertussis toxin.

Literature DB >> 1541543

Generation of human monoclonal antibodies that confer protection against pertussis toxin.

M Zaccolo¹, S Roggero, D Armellini, L Pegoraro, R Rappuoli, F Malavasi.

Abstract

A panel of human monoclonal antibodies reactive with pertussis toxin has been generated by means of Epstein-Barr virus infection. One of these, the 3F11 monoclonal antibody, showed the ability to neutralize in vitro and in vivo the toxic effects of the toxin. Western blot (immunoblot) analysis located the 3F11 epitope on the S3 subunit.

Entities: Disease Species

Mesh：

Substances：

Year: 1992 PMID： 1541543 PMCID： PMC257625 DOI： 10.1128/iai.60.3.1258-1260.1992

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

12 in total

1. Mutants of pertussis toxin suitable for vaccine development.

Authors: M Pizza; A Covacci; A Bartoloni; M Perugini; L Nencioni; M T De Magistris; L Villa; D Nucci; R Manetti; M Bugnoli
Journal: Science Date: 1989-10-27 Impact factor: 47.728

2. CD38 molecule: structural and biochemical analysis on human T lymphocytes, thymocytes, and plasma cells.

Authors: M Alessio; S Roggero; A Funaro; L B De Monte; L Peruzzi; M Geuna; F Malavasi
Journal: J Immunol Date: 1990-08-01 Impact factor: 5.422

3. Gene transfer by retrovirus-derived shuttle vectors in the generation of murine bispecific monoclonal antibodies.

Authors: L B DeMonte; P Nistico; R Tecce; P Dellabona; M Momo; A Anichini; M Mariani; P G Natali; F Malavasi
Journal: Proc Natl Acad Sci U S A Date: 1990-04 Impact factor: 11.205

4. Immunogenicity of a free synthetic peptide: carrier-conjugation enhances antibody affinity for the native protein.

Authors: M Mariani; L Bracci; R Presentini; D Nucci; P Neri; G Antoni
Journal: Mol Immunol Date: 1987-03 Impact factor: 4.407

5. Cloning and sequencing of the pertussis toxin genes: operon structure and gene duplication.

Authors: A Nicosia; M Perugini; C Franzini; M C Casagli; M G Borri; G Antoni; M Almoni; P Neri; G Ratti; R Rappuoli
Journal: Proc Natl Acad Sci U S A Date: 1986-07 Impact factor: 11.205

6. Induction of a novel morphological response in Chinese hamster ovary cells by pertussis toxin.

Authors: E L Hewlett; K T Sauer; G A Myers; J L Cowell; R L Guerrant
Journal: Infect Immun Date: 1983-06 Impact factor: 3.441

7. Monoclonal antibody against pertussis toxin: effect on toxin activity and pertussis infections.

Authors: H Sato; A Ito; J Chiba; Y Sato
Journal: Infect Immun Date: 1984-11 Impact factor: 3.441

8. Hydrophobic photolabelling of pertussis toxin subunits interacting with lipids.

Authors: C Montecucco; M Tomasi; G Schiavo; R Rappuoli
Journal: FEBS Lett Date: 1986-01-06 Impact factor: 4.124

9. Effect of monoclonal antibody to pertussis toxin on toxin activity.

Authors: H Sato; Y Sato; A Ito; I Ohishi
Journal: Infect Immun Date: 1987-04 Impact factor: 3.441

10. Metabolic, humoral, and cellular responses in adult volunteers immunized with the genetically inactivated pertussis toxin mutant PT-9K/129G.

Authors: A Podda; L Nencioni; M T De Magistris; A Di Tommaso; P Bossù; S Nuti; P Pileri; S Peppoloni; M Bugnoli; P Ruggiero
Journal: J Exp Med Date: 1990-09-01 Impact factor: 14.307

3 in total