| Literature DB >> 1541541 |
E Kim1, R I Enelow, G W Sullivan, G L Mandell.
Abstract
We measured and visualized cytosolic free calcium ([Ca2+]i) in individual human peripheral blood monocytes during phagocytosis by using the fluorescent indicator fura-2. Monocytes exhibit a rapid rise in [Ca2+]i from a basal level of 75 +/- 11 nM to a peak level of 676 +/- 78 nM (means +/- standard errors of the means; P less than 0.001) by 34 +/- 5 s after contact with opsonized zymosan particles, and a thin rim of high [Ca2+]i was observed surrounding the ingested particle.Entities:
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Year: 1992 PMID: 1541541 PMCID: PMC257622 DOI: 10.1128/iai.60.3.1244-1248.1992
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441