| Literature DB >> 1541440 |
A J Jacobs1, J A Blessing, A Munoz.
Abstract
Didemnin B was administered to 24 women with recurrent squamous cell cervical carcinoma. The initial dose was 4.2 mg/m2, intravenously, repeated every 28 days. Twenty-three patients were evaluable for toxicity and twenty-one for response. Toxicity was mild, consisting mainly of nausea and vomiting. There were no objective responses; 43% had stable disease for at least 3 months. Didemnin B, when given in this dosage schedule, appears to have minimal effect against this tumor.Entities:
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Year: 1992 PMID： 1541440 DOI： 10.1016/0090-8258(92)90055-n
Source DB: PubMed Journal: Gynecol Oncol ISSN： 0090-8258 Impact factor: 5.482