| Literature DB >> 1540839 |
G H Fisher1, I L Payan, S J Chou, E H Man, S Cerwinski, T Martin, C Emory, W H Frey.
Abstract
Normal protein-bound L-aspartyl/L-asparaginyl residues may undergo posttranslational modification by racemization to D-aspartate. Based on preliminary results reported here, proteins associated with Alzheimer neurofibrillary tangle preparations contain a greater number of these racemized D-aspartyl residues than the unaffected proteins from the surrounding gray matter or in comparable preparations from normal brains.Entities:
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Year: 1992 PMID： 1540839 DOI： 10.1016/0361-9230(92)90239-t
Source DB: PubMed Journal: Brain Res Bull ISSN： 0361-9230 Impact factor: 4.077