Literature DB >> 1540568

Exacerbation of akinetic seizures by atropine eye drops.

B D Wright1.   

Abstract

A case is reported where atropine sulphate eye drops increased the frequency of fits in a child suffering regular akinetic seizures. This increase was marked and observed during two separate courses of eye drops. This is discussed with reference to previous reports of central nervous toxicity after the use of topical atropine sulphate.

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Year:  1992        PMID： 1540568      PMCID： PMC504203          DOI： 10.1136/bjo.76.3.179

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN： 0007-1161            Impact factor:   4.638


  14 in total

1.  Toxic effects of atropine and homatropine eyedrops in children.

Authors:  D HOEFNAGEL
Journal:  N Engl J Med       Date:  1961-01-26       Impact factor: 91.245

2.  Clinical Memoranda.

Authors: 
Journal:  Br Med J       Date:  1937-03-27

3.  Death from atropine poisoning.

Authors:  W E HEATH
Journal:  Br Med J       Date:  1950-09-09

4.  The convulsant effect of topically applied atropine.

Authors:  J C Daniels; R Spehlmann
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1973-01

5.  Toxic coma induced by anticholinergic eye drops.

Authors:  J Nadal; V De la Fuente; M Abadias; J Torrent; F Jané
Journal:  Br Med J (Clin Res Ed)       Date:  1987-11-21

6.  Midline spike discharges: clinical and EEG correlates.

Authors:  R A Pourmand; O N Markand; C Thomas
Journal:  Clin Electroencephalogr       Date:  1984-10

7.  Atropine toxicity.

Authors:  P S O'Connor; J V Mumma
Journal:  Am J Ophthalmol       Date:  1985-05-15       Impact factor: 5.258

Review 8.  Systemic effects of eye drops.

Authors:  S I Davidson
Journal:  Trans Ophthalmol Soc U K       Date:  1974-07

9.  Clinical and electroencephalographic characteristics of midline parasagittal foci.

Authors:  T A Pedley; B R Tharp; K Herman
Journal:  Ann Neurol       Date:  1981-02       Impact factor: 10.422

10.  Prolonged parasympathetic paralysis and psychosis caused by atropine eye drops.

Authors:  L Harel; M Frydman; A Kauschansky
Journal:  J Pediatr Ophthalmol Strabismus       Date:  1985 Jan-Feb       Impact factor: 1.402
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  2 in total

1.  Design, pharmacokinetic, and pharmacodynamic evaluation of a new class of soft anticholinergics.

Authors:  Fenglei Huang; Clinton E Browne; Whei-Mei Wu; Attila Juhász; Fubao Ji; Nicholas Bodor
Journal:  Pharm Res       Date:  2003-10       Impact factor: 4.200

2.  Pharmacokinetic and pharmacodynamic evaluations of the zwitterionic metabolite of a new series of N-substituted soft anticholinergics.

Authors:  Whei-Mei Wu; Peter Buchwald; Nobuhiro Mori; Fubao Ji; JiaXiang Wu; Nicholas Bodor
Journal:  Pharm Res       Date:  2005-09-26       Impact factor: 4.200
  2 in total

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