Literature DB >> 1540

The prebiotic synthesis of deoxthymidine oligonucleotides. II. Comparison of condensing agents.

D G Odom, J T Brady.   

Abstract

A reaction which oligomerizes nucleotides under possible prebiotic conditions has been characterized. Nucleoside monophosphate in the presence of cyanamide at acid pH condenses to form dithymideine pyrophosphate and phosphodiester bonded compounds. Imidazole compounds and activated precursors such as nucleoside triphosphate are not necessary for this ologomerization reaction which produces primarily cyclic ologonucleotides.

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Year:  1975        PMID： 1540     DOI： 10.1007/BF01732356

Source DB:  PubMed          Journal:  J Mol Evol        ISSN： 0022-2844            Impact factor:   2.395


  17 in total

1.  CYANAMIDE: A POSSIBLE KEY COMPOUND IN CHEMICAL EVOLUTION.

Authors:  G STEINMAN; R M LEMMON; M CALVIN
Journal:  Proc Natl Acad Sci U S A       Date:  1964-07       Impact factor: 11.205

2.  Studies in experimental organic cosmochemistry.

Authors:  J ORO
Journal:  Ann N Y Acad Sci       Date:  1963-06-29       Impact factor: 5.691

3.  Prebiotic phosphorylation of thymidine at 65 degrees C in simulated desert conditions.

Authors:  M J Bishop; R Lohrmann; L E Orgel
Journal:  Nature       Date:  1972-05-19       Impact factor: 49.962

4.  Catalysts for the self-polymerization of adenosine cyclic 2', 3'-phosphate.

Authors:  M S Verlander; R Lohrmann; L E Orgel
Journal:  J Mol Evol       Date:  1973-11-27       Impact factor: 2.395

5.  The prebiotic synthesis of deoxythymidine oligonucleotides.

Authors:  E Stephen-Sherwood; D G Odom; J Oró
Journal:  J Mol Evol       Date:  1974       Impact factor: 2.395

6.  Polymerization of 5'-desoxyribonucleotides with beta-imidazolyl-4(5)-propanoic acid.

Authors:  O Pongs; P O Ts'o
Journal:  Biochem Biophys Res Commun       Date:  1969-08-07       Impact factor: 3.575

7.  Further studies of urea-catalyzed phosphorylation reactions.

Authors:  R Osterberg; L E Orgel; R Lohrmann
Journal:  J Mol Evol       Date:  1973       Impact factor: 2.395

8.  Polyphosphate and trimetaphosphate formation under potentially prebiotic conditions.

Authors:  R Osterberg; L E Orgel
Journal:  J Mol Evol       Date:  1972       Impact factor: 2.395

9.  Studies in prebiotic synthesis. V. Synthesis and photoanomerization of pyrimidine nucleosides.

Authors:  R A Sanchez; L E Orgel
Journal:  J Mol Biol       Date:  1970-02-14       Impact factor: 5.469

10.  Cyclization of the phosphate side chain of adenosine triphosphate: formation of monoadenosine 5'-trimetaphosphate.

Authors:  T Glonek; R A Kleps; T C Myers
Journal:  Science       Date:  1974-07-26       Impact factor: 47.728
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  3 in total

1.  The possible role of solid surface area in condensation reactions during chemical evolution: reevaluation.

Authors:  N Lahav; S Chang
Journal:  J Mol Evol       Date:  1976-12-30       Impact factor: 2.395

2.  The prebiotic synthesis of deoxythymidine oligonucleotides. III. Acid salt reactions.

Authors:  D G Odom; J T Brady; J Oro
Journal:  J Mol Evol       Date:  1976-03-29       Impact factor: 2.395

3.  Prebiotic nucleotide oligomerization in a fluctuating environment: effects of kaolinite and cyanamide.

Authors:  D G Odom; N Lahav; S Chang
Journal:  J Mol Evol       Date:  1979-03-15       Impact factor: 2.395
  3 in total

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