Experience with vitamin E in coronary disease.

Fifty-four patients with various classifications of angina pectoris were treated with vitamin E in a study to evaluate the effectiveness of the substance in such conditions. The incidence of improvement among patients in the series was no greater than it was in a control group not given vitamin E. As to subjective evidence of relief, there was no significant difference as between patients given vitamin E and those given placebos. When some of the patients being treated with vitamin E were given placebos, instead, for a period during the course of observation, subjective improvement was not diminished. No specific benefits attributable to vitamin E therapy could be shown.