Literature DB >> 153975

Trisomy 21 with 47,+18 lymphocyte cell line: double mitotic nondisjunction.

M B Jenkins, R L Kriel, L Boyd, A Barnwell.   

Abstract

A patient with Down's syndrome was found to have 47,XX,+18/47,XX,+21 mosaicism. Chromosome 18 trisomy was found only in 18% of lymphocytes and not in skin fibroblasts. A likely interpretation is double nondisjunction in a single lymphocyte precursor of a trisomy 21 embryo. A brief review of other cases of mitotic multiple nondisjunction and double aneuploid mosiacism is presented.

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Year:  1978        PMID： 153975      PMCID： PMC1013739          DOI： 10.1136/jmg.15.5.395

Source DB:  PubMed          Journal:  J Med Genet        ISSN： 0022-2593            Impact factor:   6.318


  24 in total

1.  Familial trisomy 7 mosaicism.

Authors:  L E DeBault; K A Halmi
Journal:  J Med Genet       Date:  1975-06       Impact factor: 6.318

2.  FAMILIAL MOSAICISM ATTRIBUTABLE TO A NEW GENE.

Authors:  H ZELLWEGER; G ABBO
Journal:  Lancet       Date:  1965-02-27       Impact factor: 79.321

3.  A CASE OF DOUBLE AUTOSOMAL TRISOMY WITH MOSAICISM: 48/XX (TRISOMY 18+21) AND 46/XX.

Authors:  L Y HSU; A J SCHWANGER; I NEMHAUSER; E H SOBEL
Journal:  J Pediatr       Date:  1965-06       Impact factor: 4.406

4.  HERMAPHRODITE WITH MOSAIC XX-XY-XXY.

Authors:  M RIBAS MUNDO; J PRATS
Journal:  Lancet       Date:  1965-09-04       Impact factor: 79.321

5.  CYTOGENETICS OF DOWN'S SYNDROME (MONGOLISM). I. DATA ON A CONSECUTIVE SERIES OF PATIENTS REFERRED FOR GENETIC COUNSELLING AND DIAGNOSIS.

Authors:  J L HAMERTON; F GIANNELLI; P E POLANI
Journal:  Cytogenetics       Date:  1965

6.  Triple chromosomal mosaic in a woman with clinical evidence of a masculinisation.

Authors:  M FRACCARO; M G BOTT; F M SALZANO; R W RUSSELL; W I CRANSTON
Journal:  Lancet       Date:  1962-06-30       Impact factor: 79.321

7.  Turner phenotype: mosaic 45,X-47,XY, plus 18.

Authors:  A Schinzel; W Schmid; A Prader
Journal:  J Med Genet       Date:  1974-03       Impact factor: 6.318

8.  Double autosomal trisomy and mosaicism for chromosomes no. 8 and no. 21.

Authors:  M G Wilson; A Fujimoto; O S Alfi
Journal:  J Med Genet       Date:  1974-03       Impact factor: 6.318

9.  Trisomy 18 mosaicism in two siblings.

Authors:  L Y Shih; L Y Hsu; E Sujansky; T Kushnick
Journal:  Clin Genet       Date:  1974       Impact factor: 4.438

10.  Aplastic anemia followed by leukemia in congenital trisomy 8 mosaicism. Ultrastructural studies of polymorphonuclear cells in peripheral blood.

Authors:  U Gafter; F Shabtal; Y Kahn; I Halbrecht; M Djaldetti
Journal:  Clin Genet       Date:  1976-02       Impact factor: 4.438
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  2 in total

1.  Trisomy 18 and trisomy 21 mosaicism in a Down's syndrome patient.

Authors:  I M Thomas; R Sayee; L Shavanthi; H Sridevi
Journal:  J Med Genet       Date:  1994-05       Impact factor: 6.318

2.  Double aneuploidy mosaicism involving chromosomes 18 and 21 in a neonate.

Authors:  Christina Mendiola; Veronica Ortega; Allison Britt; Rafael Fonseca; Gopalrao Velagaleti
Journal:  Mol Cytogenet       Date:  2022-01-24       Impact factor: 2.009
  2 in total

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