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Literature DB >> 15394072

The inhibition of streptococcal desoxyribonuclease by rabbit and human antisera.

Abstract

Rabbit antisera against partially purified streptococcal desoxyribonuclease inhibit the action of the enzyme on its substrate. The activity of pancreatic desoxyribonuclease is not affected by these antisera. Similarly antibody against pancreatic nuclease does not inhibit the streptococcal enzyme. Certain patients develop inhibitory antibody to streptococcal desoxyribonuclease following streptococcal infections, occasionally in very high titer, although the proportion of patients showing an antibody response appears to be lower than in the case of streptokinase and streptolysin O. The pattern of antibody response to desoxyribonuclease has been compared to that of streptokinase and streptolysin O in a group of ninety patients from an epidemic of scarlet fever.

Entities: Disease Species

Keywords: ENZYMES; NUCLEIC ACIDS; STREPTOCOCCI

Mesh：

Substances：

Year: 1949 PMID： 15394072 PMCID： PMC2135932 DOI： 10.1084/jem.90.6.543

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

6 in total

1. Nucleoproteins of Cell Nuclei.

Authors: A E Mirsky; A W Pollister
Journal: Proc Natl Acad Sci U S A Date: 1942-09 Impact factor: 11.205

2. QUANTITATIVE ANTISTREPTOKINASE STUDIES IN PATIENTS INFECTED WITH GROUP A HEMOLYTIC STREPTOCOCCI: A COMPARISON WITH SERUM ANTISTREPTOLYSIN AND GAMMA GLOBULIN LEVELS WITH SPECIAL REFERENCE TO THE OCCURRENCE OF RHEUMATIC FEVER.

Authors: H C Anderson; H G Kunkel; M McCarty
Journal: J Clin Invest Date: 1948-07 Impact factor: 14.808

3. [Not Available].

Authors: A CHRISTENSEN
Journal: Ugeskr Laeger Date: 1949-04-28

4. Further observations of an inhibitor in human serums of the hyaluronidase produced by a strain of hemolytic streptococcus.

Authors: G J FRIOU
Journal: J Infect Dis Date: 1949 May-Jun Impact factor: 5.226

5. The occurrence of nucleases in culture filtrates of group A hemolytic streptococci.

Authors: M McCARTY
Journal: J Exp Med Date: 1948-08 Impact factor: 14.307

6. The inhibition of d-glyceraldehyde 3-phosphate dehydrogenase by specific antiserum.

Authors: E G KREBS; V A NAJJAR
Journal: J Exp Med Date: 1948-12 Impact factor: 14.307

6 in total

29 in total

1. Simplified antistreptococcal deoxyribonuclease assay.

Authors: I OLITZKY; S BERKMAN; D BASS
Journal: J Bacteriol Date: 1962-11 Impact factor: 3.490

2. Contribution on the biochemical investigation of external factors required for type transformation in the pneumococcus.

Authors: M KOHOUTOVA
Journal: Folia Microbiol (Praha) Date: 1962-01 Impact factor: 2.099

7. Studies on desoxyribonuclease in systemic lupus erythematosus; non-participation of serum desoxyribonuclease in the L.E. phenomenon.

Authors: N B KURNICK; S PARISER; L I SCHWARTZ; S L LEE; W IRVINE
Journal: J Clin Invest Date: 1952-12 Impact factor: 14.808

The inhibition of streptococcal desoxyribonuclease by rabbit and human antisera.

1. Nucleoproteins of Cell Nuclei.

2. QUANTITATIVE ANTISTREPTOKINASE STUDIES IN PATIENTS INFECTED WITH GROUP A HEMOLYTIC STREPTOCOCCI: A COMPARISON WITH SERUM ANTISTREPTOLYSIN AND GAMMA GLOBULIN LEVELS WITH SPECIAL REFERENCE TO THE OCCURRENCE OF RHEUMATIC FEVER.

3. [Not Available].

4. Further observations of an inhibitor in human serums of the hyaluronidase produced by a strain of hemolytic streptococcus.

5. The occurrence of nucleases in culture filtrates of group A hemolytic streptococci.

6. The inhibition of d-glyceraldehyde 3-phosphate dehydrogenase by specific antiserum.

1. Simplified antistreptococcal deoxyribonuclease assay.

2. Contribution on the biochemical investigation of external factors required for type transformation in the pneumococcus.

3. Deoxyribonuclease activity of micrococci from clinical sources.

4. Observations on the diphtheria toxin-antitoxin reaction.

5. Desoxyribonuclease I activity in pancreatic disease.

6. The intravenous injection of bovine crystalline pancreatic desoxyribonuclease into patients.

7. Studies on desoxyribonuclease in systemic lupus erythematosus; non-participation of serum desoxyribonuclease in the L.E. phenomenon.

8. Staphylococcal Muller phenomenon: relationship to the plasminogen-plasmin system.

9. The extent of the enzymatic degradation of desoxyribonucleic acid (DNA) in purulent exudates by streptodornase.

10. Inhibition of streptolysin S by the serum of patients with rheumatic fever and acute streptococcal pharyngitis.