| Literature DB >> 1539073 |
S C Dilsaver1, J A Peck, D H Overstreet.
Abstract
The Flinders Sensitive Line (FSL) was derived from the Sprague-Dawley rat by selectively breeding animals with heightened sensitivity to an anticholinesterase. The FSL now consistently exhibits enhanced behavioral and physiological responses to muscarinic agonists relative to its progenitor. The authors now report the FSL exhibits enhanced thermic responsiveness to nicotine relative to the Sprague-Dawley rat. The possible relevance of this finding to investigators interested in the disorders of mood is briefly discussed.Entities:
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Year: 1992 PMID： 1539073 DOI： 10.1016/0091-3057(92)90053-i
Source DB: PubMed Journal: Pharmacol Biochem Behav ISSN： 0091-3057 Impact factor: 3.533