PURPOSE: To evaluate the relationship between delayed hyper-enhancement of the myocardium and global and regional cardiac abnormalities in hypertrophic cardiomyopathy (HCM) with asymmetrical septal hypertrophy using magnetic resonance (MR) imaging. MATERIALS AND METHODS: Twenty-three patients with HCM with asymmetrical septal hypertrophy were examined using a 1.5-T MR unit. Contrast-enhanced inversion-recovery gradient-echo imaging was performed to observe the myocardial damages associated with HCM. Balanced steady-state free precession imaging was performed to assess regional wall abnormalities and ejection fraction, and black-blood fast spin-echo imaging was performed to assess left atrial diameter. RESULTS: Delayed hyper-enhancement of the myocardium was primarily observed in the interventricular septal wall. Septal walls with the higher transmural extent of delayed hyper-enhancement were significantly thicker at end-diastole and end-systole (P < 0.05), and tended to show a decreased percentage systolic wall thickening (P = 0.079). There were no differences in theses values between non-enhancing septal walls and septal walls with the transmural extent < 50%. CONCLUSION: The high transmural extent of delayed hyper-enhancement of the myocardium may reflect the severe myocardial damage associated with the regional hypertrophy and hypokinesia in HCM. Copyright 2004 Wiley-Liss, Inc.
PURPOSE: To evaluate the relationship between delayed hyper-enhancement of the myocardium and global and regional cardiac abnormalities in hypertrophic cardiomyopathy (HCM) with asymmetrical septal hypertrophy using magnetic resonance (MR) imaging. MATERIALS AND METHODS: Twenty-three patients with HCM with asymmetrical septal hypertrophy were examined using a 1.5-T MR unit. Contrast-enhanced inversion-recovery gradient-echo imaging was performed to observe the myocardial damages associated with HCM. Balanced steady-state free precession imaging was performed to assess regional wall abnormalities and ejection fraction, and black-blood fast spin-echo imaging was performed to assess left atrial diameter. RESULTS: Delayed hyper-enhancement of the myocardium was primarily observed in the interventricular septal wall. Septal walls with the higher transmural extent of delayed hyper-enhancement were significantly thicker at end-diastole and end-systole (P < 0.05), and tended to show a decreased percentage systolic wall thickening (P = 0.079). There were no differences in theses values between non-enhancing septal walls and septal walls with the transmural extent < 50%. CONCLUSION: The high transmural extent of delayed hyper-enhancement of the myocardium may reflect the severe myocardial damage associated with the regional hypertrophy and hypokinesia in HCM. Copyright 2004 Wiley-Liss, Inc.
Authors: Annamalai Senthilkumar; Maulik D Majmudar; Chetan Shenoy; Han W Kim; Raymond J Kim Journal: Heart Fail Clin Date: 2009-07 Impact factor: 3.179
Authors: Radwa A Noureldin; Songtao Liu; Marcelo S Nacif; Daniel P Judge; Marc K Halushka; Theodore P Abraham; Carolyn Ho; David A Bluemke Journal: J Cardiovasc Magn Reson Date: 2012-02-20 Impact factor: 5.364
Authors: A Chiribiri; S Leuzzi; M R Conte; S Bongioanni; K Bratis; L Olivotti; C De Rosa; E Lardone; P Di Donna; A D M Villa; F Cesarani; E Nagel; F Gaita; R Bonamini Journal: Clin Radiol Date: 2015-02-07 Impact factor: 2.350