Literature DB >> 15389754

A genome scan of neuroticism in nicotine dependent smokers.

Benjamin M Neale1, Patrick F Sullivan, Kenneth S Kendler.   

Abstract

Neuroticism is a personality factor that has consistently been demonstrated to be associated with anxiety, depression, and other "internalizing" disorders. We analyzed a genome scan for neuroticism on a sample of 129 sib-pair families (113 with a single sibling pair, 18 with multiple sibling pairs) containing a total of 201 possible sibling pairs, ascertained for concordance on nicotine dependence. Using Merlin-Regress, we replicated peaks for neuroticism described by prior studies, on chromosomes 1 and 11 with LOD scores of 2.52 and 1.97 (P-value of 0.003 and 0.0108) respectively, and have some evidence for a novel finding on chromosome 12 with a LOD of 2.85 (P-value of 0.0014). Copyright 2004 Wiley-Liss, Inc.

Entities:  

Mesh：

Year:  2005        PMID： 15389754     DOI： 10.1002/ajmg.b.30095

Source DB:  PubMed          Journal:  Am J Med Genet B Neuropsychiatr Genet        ISSN： 1552-4841            Impact factor:   3.568


  14 in total

1.  A whole genome association study of neuroticism using DNA pooling.

Authors:  S Shifman; A Bhomra; S Smiley; N R Wray; M R James; N G Martin; J M Hettema; S S An; M C Neale; E J C G van den Oord; K S Kendler; X Chen; D I Boomsma; C M Middeldorp; J J Hottenga; P E Slagboom; J Flint
Journal:  Mol Psychiatry       Date:  2007-07-31       Impact factor: 15.992

2.  Meta-analyses of genome-wide linkage scans of anxiety-related phenotypes.

Authors:  Bradley T Webb; An-Yuan Guo; Brion S Maher; Zhongming Zhao; Edwin J van den Oord; Kenneth S Kendler; Brien P Riley; Nathan A Gillespie; Carol A Prescott; Christel M Middeldorp; Gonneke Willemsen; Eco Jc de Geus; Jouke-Jan Hottenga; Dorret I Boomsma; Eline P Slagboom; Naomi R Wray; Grant W Montgomery; Nicholas G Martin; Margie J Wright; Andrew C Heath; Pamela A Madden; Joel Gelernter; James A Knowles; Steven P Hamilton; Myrna M Weissman; Abby J Fyer; Patricia Huezo-Diaz; Peter McGuffin; Anne Farmer; Ian W Craig; Cathryn Lewis; Pak Sham; Raymond R Crowe; Jonathan Flint; John M Hettema
Journal:  Eur J Hum Genet       Date:  2012-04-04       Impact factor: 4.246

3.  Risk factors influencing smoking behavior: a Turkish twin study.

Authors:  Sevgi Yurt Oncel; Danielle M Dick; Hermine H Maes; Fazil Alıev
Journal:  Twin Res Hum Genet       Date:  2014-12       Impact factor: 1.587

4.  A genome-wide association study of Cloninger's temperament scales: implications for the evolutionary genetics of personality.

Authors:  Karin J H Verweij; Brendan P Zietsch; Sarah E Medland; Scott D Gordon; Beben Benyamin; Dale R Nyholt; Brian P McEvoy; Patrick F Sullivan; Andrew C Heath; Pamela A F Madden; Anjali K Henders; Grant W Montgomery; Nicholas G Martin; Naomi R Wray
Journal:  Biol Psychol       Date:  2010-08-04       Impact factor: 3.251

5.  Genome-wide association scan for five major dimensions of personality.

Authors:  A Terracciano; S Sanna; M Uda; B Deiana; G Usala; F Busonero; A Maschio; M Scally; N Patriciu; W-M Chen; M A Distel; E P Slagboom; D I Boomsma; S Villafuerte; E Sliwerska; M Burmeister; N Amin; A C J W Janssens; C M van Duijn; D Schlessinger; G R Abecasis; P T Costa
Journal:  Mol Psychiatry       Date:  2008-10-28       Impact factor: 15.992

6.  A genome-wide association study of neuroticism in a population-based sample.

Authors:  Federico C F Calboli; Federica Tozzi; Nicholas W Galwey; Athos Antoniades; Vincent Mooser; Martin Preisig; Peter Vollenweider; Dawn Waterworth; Gerard Waeber; Michael R Johnson; Pierandrea Muglia; David J Balding
Journal:  PLoS One       Date:  2010-07-09       Impact factor: 3.240

7.  Suggestive linkage on chromosome 2, 8, and 17 for lifetime major depression.

Authors:  Christel M Middeldorp; Patrick F Sullivan; Naomi R Wray; Jouke-Jan Hottenga; Eco J C de Geus; Mireille van den Berg; Grant W Montgomery; Will L Coventry; Dixie J Statham; Gavin Andrews; P Eline Slagboom; Dorret I Boomsma; Nicholas G Martin
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2009-04-05       Impact factor: 3.568

8.  Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands.

Authors:  Naomi R Wray; Christel M Middeldorp; Andrew J Birley; Scott D Gordon; Patrick F Sullivan; Peter M Visscher; Dale R Nyholt; Gonneke Willemsen; Eco J C de Geus; P Eline Slagboom; Grant W Montgomery; Nicholas G Martin; Dorret I Boomsma
Journal:  Arch Gen Psychiatry       Date:  2008-06

Review 9.  Uncovering the Genetic Architecture of Major Depression.

Authors:  Andrew M McIntosh; Patrick F Sullivan; Cathryn M Lewis
Journal:  Neuron       Date:  2019-04-03       Impact factor: 17.173

10.  Meta-analysis of genome-wide association studies for personality.

Authors:  M H M de Moor; P T Costa; A Terracciano; R F Krueger; E J C de Geus; T Toshiko; B W J H Penninx; T Esko; P A F Madden; J Derringer; N Amin; G Willemsen; J-J Hottenga; M A Distel; M Uda; S Sanna; P Spinhoven; C A Hartman; P Sullivan; A Realo; J Allik; A C Heath; M L Pergadia; A Agrawal; P Lin; R Grucza; T Nutile; M Ciullo; D Rujescu; I Giegling; B Konte; E Widen; D L Cousminer; J G Eriksson; A Palotie; L Peltonen; M Luciano; A Tenesa; G Davies; L M Lopez; N K Hansell; S E Medland; L Ferrucci; D Schlessinger; G W Montgomery; M J Wright; Y S Aulchenko; A C J W Janssens; B A Oostra; A Metspalu; G R Abecasis; I J Deary; K Räikkönen; L J Bierut; N G Martin; C M van Duijn; D I Boomsma
Journal:  Mol Psychiatry       Date:  2010-12-21       Impact factor: 15.992
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