Literature DB >> 15387637

Tethered lipids from Thapsia garganica.

Huizhen Liu1, Carl Erik Olsen, S Brøgger Christensen.   

Abstract

The two macrocyclic lipids 2-hydroxymethyl-1,4-dioxacycloicosane-5,20-dione (1) and 3-hydroxy-1,5-dioxacyclohenicosane-6,21-dione (2) have been isolated from the fruits of Thapsia garganica. Tethered lipids are unprecedented in the plant kingdom.

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Year:  2004        PMID： 15387637     DOI： 10.1021/np049781y

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  2 in total

Review 1.  Targeting thapsigargin towards tumors.

Authors:  Nhu Thi Quynh Doan; Eleonora Sandholdt Paulsen; Pankaj Sehgal; Jesper Vuust Møller; Poul Nissen; Samuel R Denmeade; John T Isaacs; Craig A Dionne; Søren Brøgger Christensen
Journal:  Steroids       Date:  2014-07-24       Impact factor: 2.668

2.  From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development.

Authors:  Søren Brøgger Christensen; Henrik Toft Simonsen; Nikolai Engedal; Poul Nissen; Jesper Vuust Møller; Samuel R Denmeade; John T Isaacs
Journal:  Prog Chem Org Nat Prod       Date:  2021
  2 in total

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