| Literature DB >> 15385525 |
Axana Haggar1, Cecilia Ehrnfelt, Jan Holgersson, Jan-Ingmar Flock.
Abstract
Extracellular adherence protein (Eap) from Staphylococcus aureus inhibits the adherence of neutrophils to nonstimulated and tumor necrosis factor alpha-stimulated endothelial cells in both static adhesion assays and flow adhesion assays. Consequently, Eap also impaired their transendothelial migration. During an S. aureus infection, Eap may thus serve to reduce inflammation by inhibiting neutrophil adhesion and extravasation.Entities:
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Year: 2004 PMID: 15385525 PMCID: PMC517550 DOI: 10.1128/IAI.72.10.6164-6167.2004
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441