OBJECTIVE: FDG PET is frequently used as part of the diagnostic workup in cancer patients. Visualization of radiotracer-avid foci suggests the presence of malignant disease. Unexplained focal FDG accumulation in the abdomen is sometimes noted, but the clinical significance of this finding is unknown. Therefore, we followed cases with unexplained focal abdominal FDG uptake found incidentally on whole-body scans to define the cause and clinical significance of this finding. CONCLUSION: Unexplained focal abdominal FDG uptake is an unusual finding with causes that include malignant and benign processes. Among the 14 cases with definitive diagnoses, seven were adenomas, which is a premalignant condition, and five (35.7%) were malignant. Therefore, although rare, unexplained focal abdominal FDG uptake should not be ignored and further diagnostic workup is warranted.
OBJECTIVE:FDG PET is frequently used as part of the diagnostic workup in cancerpatients. Visualization of radiotracer-avid foci suggests the presence of malignant disease. Unexplained focal FDG accumulation in the abdomen is sometimes noted, but the clinical significance of this finding is unknown. Therefore, we followed cases with unexplained focal abdominal FDG uptake found incidentally on whole-body scans to define the cause and clinical significance of this finding. CONCLUSION: Unexplained focal abdominal FDG uptake is an unusual finding with causes that include malignant and benign processes. Among the 14 cases with definitive diagnoses, seven were adenomas, which is a premalignant condition, and five (35.7%) were malignant. Therefore, although rare, unexplained focal abdominal FDG uptake should not be ignored and further diagnostic workup is warranted.
Authors: Dushyant V Sahani; Pietro A Bonaffini; Onofrio A Catalano; Alexander R Guimaraes; Michael A Blake Journal: Radiographics Date: 2012 Jul-Aug Impact factor: 5.333
Authors: S T Lee; T Tan; A M T Poon; H B Toh; S Gill; S U Berlangieri; E Kraft; A J Byrne; K Pathmaraj; G J O'Keefe; N Tebbutt; A M Scott Journal: Mol Imaging Biol Date: 2007-11-10 Impact factor: 3.488
Authors: Sara Khademi; Antonio C Westphalen; Emily M Webb; Bonnie N Joe; Shiva Badiee; Randy A Hawkins; Fergus V Coakley Journal: Clin Imaging Date: 2009 Jan-Feb Impact factor: 1.605
Authors: Sun Hee Roh; Sung-Ae Jung; Seong-Eun Kim; Hye-In Kim; Min Jin Lee; Chung Hyun Tae; Ju Young Choi; Ki-Nam Shim; Hye-Kyung Jung; Tae Hun Kim; Kwon Yoo; Il Hwan Moon; Bom Sahn Kim Journal: Clin Endosc Date: 2012-06-30