BACKGROUND: Embryonal rhabdomyosarcoma (sarcoma botryoides) of the female genital tract is rare in the cervix. It tends to occur in children and young women, and appears to have a better prognosis than sarcoma botryoides of the vagina and uterus. CASE: We report a case of embryonal rhabdomyosarcoma (sarcoma botryoides) presenting as a cervical polyp in a 19-year-old female. The tumor was composed of rhabdomyoblasts of varying differentiation dispersed within a loose, myxoid stroma, and formed a distinct 'cambium' layer beneath the epithelium. The patient was successfully treated with fertility-sparing surgery and adjuvant chemotherapy. CONCLUSIONS: Awareness of this uncommon lesion in this site and its clinical implications is important to avoid misdiagnosis. Therapy has recently inclined towards conservative treatment.
BACKGROUND:Embryonal rhabdomyosarcoma (sarcoma botryoides) of the female genital tract is rare in the cervix. It tends to occur in children and young women, and appears to have a better prognosis than sarcoma botryoides of the vagina and uterus. CASE: We report a case of embryonal rhabdomyosarcoma (sarcoma botryoides) presenting as a cervical polyp in a 19-year-old female. The tumor was composed of rhabdomyoblasts of varying differentiation dispersed within a loose, myxoid stroma, and formed a distinct 'cambium' layer beneath the epithelium. The patient was successfully treated with fertility-sparing surgery and adjuvant chemotherapy. CONCLUSIONS: Awareness of this uncommon lesion in this site and its clinical implications is important to avoid misdiagnosis. Therapy has recently inclined towards conservative treatment.
Authors: Mark L Kayton; Leonard H Wexler; Sharyn N Lewin; Kay J Park; Michael P La Quaglia; Nadeem R Abu-Rustum Journal: J Pediatr Surg Date: 2009-04 Impact factor: 2.545