Literature DB >> 15381132

Multitargeted drugs: the end of the "one-target-one-disease" philosophy?

Camille G Wermuth.   

Abstract

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Year:  2004        PMID： 15381132     DOI： 10.1016/S1359-6446(04)03213-1

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


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  24 in total

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Journal:  Protein Cell       Date:  2012-03-17       Impact factor: 14.870

Review 2.  Network-based approaches in drug discovery and early development.

Authors:  J M Harrold; M Ramanathan; D E Mager
Journal:  Clin Pharmacol Ther       Date:  2013-09-11       Impact factor: 6.875

3.  Molecular network-based analysis of guizhi-shaoyao-zhimu decoction, a TCM herbal formula, for treatment of diabetic peripheral neuropathy.

Authors:  Ning Zhao; Jian Li; Li Li; Xu-yan Niu; Miao Jiang; Xiao-juan He; Zhao-xiang Bian; Ge Zhang; Ai-ping Lu
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4.  A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids.

Authors:  Mingzhao Zhu; Wayne D Harshbarger; Omar Robles; Joanna Krysiak; Kenneth G Hull; Sung Wook Cho; Robyn D Richardson; Yanyan Yang; Andres Garcia; Lindsey Spiegelman; Bianca Ramirez; Christopher T Wilson; Ju Anne Yau; James T Moore; Caitlen B Walker; James C Sacchettini; Wenshe R Liu; Stephan A Sieber; Jeffrey W Smith; Daniel Romo
Journal:  Bioorg Med Chem       Date:  2017-01-19       Impact factor: 3.641

Review 5.  Integration of Chinese medicine with Western medicine could lead to future medicine: molecular module medicine.

Authors:  Chi Zhang; Ge Zhang; Ke-ji Chen; Ai-ping Lu
Journal:  Chin J Integr Med       Date:  2016-04-09       Impact factor: 1.978

6.  Withania somnifera Improves Ischemic Stroke Outcomes by Attenuating PARP1-AIF-Mediated Caspase-Independent Apoptosis.

Authors:  Aparna Raghavan; Zahoor A Shah
Journal:  Mol Neurobiol       Date:  2014-10-08       Impact factor: 5.590

Review 7.  Molecular networks in drug discovery.

Authors:  John Kenneth Morrow; Longzhang Tian; Shuxing Zhang
Journal:  Crit Rev Biomed Eng       Date:  2010

8.  Bamboo leaf extract improves spatial learning ability in a rat model with senile dementia.

Authors:  Jian-xiang Liu; Min-ying Zhu; Ci-yuan Feng; Hai-bin Ding; Ying Zhan; Zhan Zhao; Yue-min Ding
Journal:  J Zhejiang Univ Sci B       Date:  2015-07       Impact factor: 3.066

9.  Identification of diaryl 5-amino-1,2,4-oxadiazoles as tubulin inhibitors: the special case of 3-(2-fluorophenyl)-5-(4-methoxyphenyl)amino-1,2,4-oxadiazole.

Authors:  Andrei A Gakh; Andrey V Sosnov; Mikhail Krasavin; Tam Luong Nguyen; Ernest Hamel
Journal:  Bioorg Med Chem Lett       Date:  2013-01-11       Impact factor: 2.823

10.  Ashwagandha root in the treatment of non-classical adrenal hyperplasia.

Authors:  Amir Kalani; Gul Bahtiyar; Alan Sacerdote
Journal:  BMJ Case Rep       Date:  2012-09-17
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