| Literature DB >> 15380649 |
Mark Shamtsyan1, Valentina Konusova, Yulia Maksimova, Alexander Goloshchev, Andrey Panchenko, Andrey Simbirtsev, Nikolay Petrishchev, Nina Denisova.
Abstract
Aqueous extracts from fruit bodies and mycelia of various higher Basidiomycetes were studied in search for reliable biological effects. In vitro and in vivo experiments were conducted. The results showed that the aqueous extracts demonstrated various types of marked biological actions: an increased production of reactive oxygen forms by neutrophil cells of human peripheral blood; a significant mitogenic activity in a wide range of concentrations; stimulation on production of inflammatory cytokines interleukine 1-beta and interleukine-8 by peripheral blood cells; a decrease in both average tumor size in mice with transplanted melanoma B16 and a manifestation of tumorous intoxication; and a prolongation in the survival rate of such mice.Entities:
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Year: 2004 PMID： 15380649 DOI： 10.1016/j.jbiotec.2004.04.034
Source DB: PubMed Journal: J Biotechnol ISSN： 0168-1656 Impact factor: 3.307