Literature DB >> 15377502

The Los Alamos hepatitis C sequence database.

Carla Kuiken1, Karina Yusim, Laura Boykin, Russell Richardson.   

Abstract

MOTIVATION: The hepatitis C virus (HCV) is a significant threat to public health worldwide. The virus is highly variable and evolves rapidly, making it an elusive target for the immune system and for vaccine and drug design. At present, some 30 000 HCV sequences have been published. A central website that provides annotated sequences and analysis tools will be helpful to HCV scientists worldwide.
RESULTS: The HCV sequence database collects and annotates sequence data and provides them to the public via a website that contains a user-friendly search interface and a large number of sequence analysis tools, based on the model of the highly regarded Los Alamos HIV database. The HCV sequence database was officially launched in September 2003. Since then, its usage has steadily increased and is now at an average of approximately 280 visits per day from distinct IP addresses. AVAILABILITY: The HCV website can be accessed via http://hcv.lanl.gov and http://hcv-db.org.

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Year:  2004        PMID: 15377502     DOI: 10.1093/bioinformatics/bth485

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  169 in total

1.  Construction of a chimeric hepatitis C virus replicon based on a strain isolated from a chronic hepatitis C patient.

Authors:  Huang Cao; Wandi Zhu; Qingxia Han; Rongjuan Pei; Xinwen Chen
Journal:  Virol Sin       Date:  2014-01-20       Impact factor: 4.327

2.  Statistical linkage analysis of substitutions in patient-derived sequences of genotype 1a hepatitis C virus nonstructural protein 3 exposes targets for immunogen design.

Authors:  Ahmed A Quadeer; Raymond H Y Louie; Karthik Shekhar; Arup K Chakraborty; I-Ming Hsing; Matthew R McKay
Journal:  J Virol       Date:  2014-04-23       Impact factor: 5.103

3.  Immunologic evidence for lack of heterologous protection following resolution of HCV in patients with non-genotype 1 infection.

Authors:  Julian Schulze Zur Wiesch; Georg M Lauer; Joerg Timm; Thomas Kuntzen; Martin Neukamm; Andrew Berical; Andrea M Jones; Brian E Nolan; Steve A Longworth; Victoria Kasprowicz; Cory McMahon; Alysse Wurcel; Ansgar W Lohse; Lia L Lewis-Ximenez; Raymond T Chung; Arthur Y Kim; Todd M Allen; Bruce D Walker
Journal:  Blood       Date:  2007-05-02       Impact factor: 22.113

Review 4.  Sequence diversity of hepatitis C virus: implications for immune control and therapy.

Authors:  Joerg Timm; Michael Roggendorf
Journal:  World J Gastroenterol       Date:  2007-09-28       Impact factor: 5.742

5.  Sequencing assays for failed genotyping with the versant hepatitis C virus genotype assay (LiPA), version 2.0.

Authors:  Sylvie Larrat; Jean-Dominique Poveda; Camille Coudret; Katia Fusillier; Nelly Magnat; Anne Signori-Schmuck; Vincent Thibault; Patrice Morand
Journal:  J Clin Microbiol       Date:  2013-04-24       Impact factor: 5.948

6.  Contribution of genome-wide HCV genetic differences to outcome of interferon-based therapy in Caucasian American and African American patients.

Authors:  Maureen J Donlin; Nathan A Cannon; Rajeev Aurora; Jia Li; Abdus S Wahed; Adrian M Di Bisceglie; John E Tavis
Journal:  PLoS One       Date:  2010-02-03       Impact factor: 3.240

7.  A classification approach for genotyping viral sequences based on multidimensional scaling and linear discriminant analysis.

Authors:  Jiwoong Kim; Yongju Ahn; Kichan Lee; Sung Hee Park; Sangsoo Kim
Journal:  BMC Bioinformatics       Date:  2010-08-21       Impact factor: 3.169

8.  RotaC: a web-based tool for the complete genome classification of group A rotaviruses.

Authors:  Piet Maes; Jelle Matthijnssens; Mustafizur Rahman; Marc Van Ranst
Journal:  BMC Microbiol       Date:  2009-11-23       Impact factor: 3.605

9.  Evidence of recombination in Hepatitis C Virus populations infecting a hemophiliac patient.

Authors:  Pilar Moreno; Macarena Alvarez; Lilia López; Gonzalo Moratorio; Didier Casane; Matías Castells; Silvia Castro; Juan Cristina; Rodney Colina
Journal:  Virol J       Date:  2009-11-18       Impact factor: 4.099

10.  HCV genotyping using statistical classification approach.

Authors:  Ping Qiu; Xiao-Yan Cai; Wei Ding; Qing Zhang; Ellie D Norris; Jonathan R Greene
Journal:  J Biomed Sci       Date:  2009-07-08       Impact factor: 8.410

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