Literature DB >> 1537645

Relationship between precorneal retention of viscous eye drops and tear fluid composition.

A Ludwig1, N J van Haeringen, V M Bodelier, M Van Ooteghem.   

Abstract

The influence of viscolysers on the precorneal residence of a fluorescent tracer was determined, using slit lamp fluorophotometry. The solution acceptability was evaluated by the volunteers by answering a standard questionnaire. The relationship between precorneal retention of viscous eye drops, discomfort and tear fluid composition after instillation of various cellulosic solutions was examined. Irritating hydroxypropylcellulose solution increases the total protein concentration of tears, without change in the ratio of lysozyme to total protein.

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Year:  1992        PMID： 1537645     DOI： 10.1007/bf00917068

Source DB:  PubMed          Journal:  Int Ophthalmol        ISSN： 0165-5701            Impact factor:   2.031


  7 in total

1.  Corneal contact times of ophthalmic vehicles. Evaluation by microscintigraphy.

Authors:  J H Trueblood; R M Rossomondo; L A Wilson; W H Carlton
Journal:  Arch Ophthalmol       Date:  1975-02

2.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

Authors:  M M Bradford
Journal:  Anal Biochem       Date:  1976-05-07       Impact factor: 3.365

3.  Tear film stability and tear surface tension.

Authors:  J M Tiffany; N Winter; G Bliss
Journal:  Curr Eye Res       Date:  1989-05       Impact factor: 2.424

4.  Influence of the surface tension of eye drops on the retention of a tracer in the precorneal area of human eyes.

Authors:  A Ludwig; M Van Ooteghem
Journal:  J Pharm Belg       Date:  1988 May-Jun

5.  The study of the precorneal dynamics of ophthalmic solutions by fluorophotometry.

Authors:  A Ludwig; M Van Ooteghem
Journal:  Pharm Acta Helv       Date:  1986

6.  Relationship of viscosity, contact time and prolongation of action of methylcellulose-containing ophthalmic solutions.

Authors:  S M Blaug; A T Canada
Journal:  Am J Hosp Pharm       Date:  1965-12

7.  Effects of drug vehicles on ocular contact time.

Authors:  R Hardberger; C Hanna; C M Boyd
Journal:  Arch Ophthalmol       Date:  1975-01
  7 in total
  1 in total

1.  Modelling ocular pharmacokinetics of fluorescein administered as lyophilisate or conventional eye drops.

Authors:  Khaled Abduljalil; Michael Diestelhorst; Oxana Doroshyenko; Anja Lux; Andre Steinfeld; Sven Dinslage; Richard Süverkrüp; Uwe Fuhr
Journal:  Eur J Clin Pharmacol       Date:  2008-01-25       Impact factor: 2.953
  1 in total

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