Literature DB >> 1537463

Cytochrome P450 and the arachidonate cascade.

J H Capdevila1, J R Falck, R W Estabrook.   

Abstract

Arachidonic acid and many products of the arachidonate cascade serve as substrates for cytochrome P450-mediated metabolism via allylic oxidation, omega hydroxylation, and epoxygenation as well as peroxide rearrangement. Defining the physiological importance of these metabolites is an area of intense research interest. Cytochrome P450-catalyzed reactions play prominent roles in multiplying the structural and functional diversity of the arachidonate metabolic cascade.

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Year:  1992        PMID： 1537463     DOI： 10.1096/fasebj.6.2.1537463

Source DB:  PubMed          Journal:  FASEB J        ISSN： 0892-6638            Impact factor:   5.191


  62 in total

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10.  Effect of ethanol on cytochrome P450 in the rat brain.

Authors:  M Warner; J A Gustafsson
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