Literature DB >> 15372851

The care gap: underuse of statin therapy in the elderly.

A Gaw1.   

Abstract

Atherosclerotic diseases are responsible for the majority of deaths in the elderly, and they can also increase the risk of disability. Statins are first-line therapies for lowering lipid levels and have been shown to reduce the risk of cardiovascular events in large-scale clinical trials. There is a growing body of evidence that statins are as efficacious at lowering lipid levels and reducing the risk of coronary heart disease (CHD) in elderly patients as in younger individuals. Furthermore, as this population is at a greater absolute risk of CHD, they may receive greater absolute benefits from treatment. However, despite these benefits, many elderly individuals at risk of CHD and stroke are not receiving adequate lipid-lowering therapy, which could help them to maintain their health and independence. Further, prospective randomised trials are required to guide physicians in the treatment of elderly patients at risk of atherosclerotic disease, thereby resolving the current undertreatment.

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Year:  2004        PMID: 15372851     DOI: 10.1111/j.1368-5031.2004.00300.x

Source DB:  PubMed          Journal:  Int J Clin Pract        ISSN: 1368-5031            Impact factor:   2.503


  9 in total

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2.  Preventive medicine in the older patient: a United kingdom perspective.

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Journal:  Int J Prev Med       Date:  2012-06

3.  The comparative efficacy of ezetimibe added to atorvastatin 10 mg versus uptitration to atorvastatin 40 mg in subgroups of patients aged 65 to 74 years or greater than or equal to 75 years.

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Review 4.  How important is diabetes as a risk factor for cardiovascular and other diseases in older adults?

Authors:  Andre Pascal Kengne; Anushka Patel
Journal:  PLoS Med       Date:  2006-10       Impact factor: 11.069

5.  Early efficacy and safety of statin therapy in Korean patients with hypercholesterolemia: Daegu and Gyeongbuk Statin Registry.

Authors:  Han Joon Bae; Yun-Kyeong Cho; Hyoung-Seob Park; Hyuck-Jun Yoon; Hyungseop Kim; Seongwook Han; Seung-Ho Hur; Yoon-Nyun Kim; Kwon-Bae Kim; Jae-Kean Ryu; Deug Young Nah; Chang-Wook Nam
Journal:  Korean J Intern Med       Date:  2019-08-19       Impact factor: 2.884

6.  Under-prescription of medications in older adults according to START criteria: A cross-sectional study in Lebanon.

Authors:  Venise Hanna; Bahia Chahine; Farah Al Souheil
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7.  Underinvestigation and undertreatment of carotid disease in elderly patients with transient ischaemic attack and stroke: comparative population based study.

Authors:  Jack F Fairhead; Peter M Rothwell
Journal:  BMJ       Date:  2006-07-18

8.  Medication Underuse in Aging Outpatients with Cardiovascular Disease: Prevalence, Determinants, and Outcomes in a Prospective Cohort Study.

Authors:  Andreas D Meid; Renate Quinzler; Julia Freigofas; Kai-Uwe Saum; Ben Schöttker; Bernd Holleczek; Dirk Heider; Hans-Helmut König; Hermann Brenner; Walter E Haefeli
Journal:  PLoS One       Date:  2015-08-19       Impact factor: 3.240

9.  Factors associated with statin treatment for the primary prevention of cardiovascular disease in people within 2 years following diagnosis of diabetes in Scotland, 2006-2008.

Authors:  N R V Jones; C M Fischbacher; B Guthrie; G Leese; R S Lindsay; J A McKnight; D Pearson; S Philip; N Sattar; S H Wild
Journal:  Diabet Med       Date:  2014-03-24       Impact factor: 4.359

  9 in total

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