Literature DB >> 15371713

Spinal arthrodesis with instrumentation for thoracolumbar kyphosis in pediatric achondroplasia.

Michael C Ain1, James A Browne.   

Abstract

STUDY
DESIGN: Retrospective radiograph and chart review.
OBJECTIVES: To assess the safety, efficacy, and complications after posterior spinal arthrodesis with instrumentation for thoracolumbar kyphosis in the pediatric achondroplast. SUMMARY OF BACKGROUND DATA: The conventional approach of anterior and posterior arthrodesis has achieved minimal correction, avoided instrumentation, and had a high risk of neurologic deterioration. To the current authors' knowledge, there are only two reports of successful instrumentation with pedicle screw fixation for kyphosis in pediatric achondroplasts; the outcome of such procedures remains largely unknown.
METHODS: The current authors evaluated the results of posterior spinal arthrodeses with instrumentation performed between 1998 and 2001 on 12 consecutive patients (mean age, 12 years). Indications for arthrodesis were concomitant laminectomy for neurologic symptoms or progressive deformity. Arthrodesis methods included anterior and posterior arthrodesis (5 patients) and posterior arthrodesis only (7 patients). Intraoperative somatosensory-evoked potentials, pedicle screw stimulation, and/or a wake-up test were used to confirm neurologic status in all patients.
RESULTS: Successful fusion was obtained in all patients. No intraoperative or postoperative neurologic deterioration was encountered. Mean improvement in kyphotic deformity was 50%. Complications included three instrumentation fractures (2 patients) and one dural leak. Parents rated outcome as excellent (4), good (6), and fair (2). No patients have subsequently experienced deformity progression.
CONCLUSIONS: Spinal arthrodesis with vertebral body and/or pedicle screw instrumentation was a reliable technique for treating thoracolumbar kyphosis in achondroplasia and did not precipitate any of the neuromonitoring difficulties or neurologic deficits that have been reported in previous studies.

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Year:  2004        PMID: 15371713     DOI: 10.1097/01.brs.0000138411.14588.47

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  10 in total

1.  Complications associated with thoracic pedicle screws in spinal deformity.

Authors:  Gang Li; Guohua Lv; Peter Passias; Michal Kozanek; Umesh S Metkar; Zhongjun Liu; Kirkham B Wood; Lubos Rehak; Youwen Deng
Journal:  Eur Spine J       Date:  2010-03-17       Impact factor: 3.134

2.  Surgical treatment of a 180° thoracolumbar fixed kyphosis in a young achondroplastic patient: a one-stage "in situ" combined fusion and spinal cord translocation.

Authors:  J C Aurégan; T Odent; M Zerah; J P Padovani; C Glorion
Journal:  Eur Spine J       Date:  2010-08-17       Impact factor: 3.134

3.  Long-Term Results of Posterior Vertebral Column Resection for Severe Thoracolumbar Kyphosis with Achondroplastic Patients: A Case Series.

Authors:  Masato Tanaka; Tsang-Tung Chan; Haruo Misawa; Koji Uotani; Shinaya Arataki; Tomoyuki Takigawa; Tetsuro Mazaki; Yoshihisa Sugimoto
Journal:  Medicina (Kaunas)       Date:  2022-04-27       Impact factor: 2.948

4.  Combined spinal arthrodesis with instrumentation for the management of progressive thoracolumbar kyphosis in children with mucopolysaccharidosis.

Authors:  Enrique Garrido; Félix Tomé-Bermejo; Christopher I Adams
Journal:  Eur Spine J       Date:  2014-01-28       Impact factor: 3.134

Review 5.  Achondroplasia: a comprehensive clinical review.

Authors:  Richard M Pauli
Journal:  Orphanet J Rare Dis       Date:  2019-01-03       Impact factor: 4.123

6.  Surgical management of thoracolumbar kyphosis in mucopolysaccharidosis type 1 in a reference center.

Authors:  Kariman Abelin Genevois; Christophe Garin; Federico Solla; Nathalie Guffon; Rémi Kohler
Journal:  J Inherit Metab Dis       Date:  2013-06-29       Impact factor: 4.982

7.  Kyphectomy for severe kyphosis with pyogenic spondylitis associated with myelomeningocele: a case report.

Authors:  Kenji Yoshioka; Kota Watanabe; Yoshiaki Toyama; Kazuhiro Chiba; Morio Matsumoto
Journal:  Scoliosis       Date:  2011-04-08

8.  Best practice guidelines for management of spinal disorders in skeletal dysplasia.

Authors:  Klane K White; Michael B Bober; Tae-Joon Cho; Michael J Goldberg; Julie Hoover-Fong; Melita Irving; Shawn E Kamps; William G Mackenzie; Cathleen Raggio; Samantha A Spencer; Viviana Bompadre; Ravi Savarirayan
Journal:  Orphanet J Rare Dis       Date:  2020-06-24       Impact factor: 4.123

9.  Sagittal alignment at 3 years old determines future thoracolumbar kyphosis in achondroplasia: A prospective study with minimum 5-year follow-up from infancy.

Authors:  Kei Ando; Kazuyoshi Kobayashi; Hiroaki Nakashima; Masaaki Machino; Sadayuki Ito; Shunsuke Kanbara; Taro Inoue; Naoki Segi; Hiroyuki Koshimizu; Shiro Imagama
Journal:  N Am Spine Soc J       Date:  2021-05-13

10.  Spondylectomy and lateral lumbar interbody fusion for thoracolumbar kyphosis in an adult with achondroplasia: A case report.

Authors:  Masashi Miyazaki; Shozo Kanezaki; Naoki Notani; Toshinobu Ishihara; Hiroshi Tsumura
Journal:  Medicine (Baltimore)       Date:  2017-12       Impact factor: 1.817

  10 in total

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