Literature DB >> 15371639

Self-similar mitochondrial DNA.

Nestor N Oiwa1, James A Glazier.   

Abstract

We show that repeated sequences, like palindromes (local repetitions) and homologies between two different nucleotide sequences (motifs along the genome), compose a self-similar (fractal) pattern in mitochondrial DNA. This self-similarity comes from the looplike structures distributed along the genome. The looplike structures generate scaling laws in a pseudorandom DNA walk constructed from the sequence, called a Lévy flight. We measure the scaling laws from the generalized fractal dimension and singularity spectrum for mitochondrial DNA walks for 35 different species. In particular, we report characteristic loop distributions for mammal mitochondrial genomes.

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Year:  2004        PMID: 15371639     DOI: 10.1385/CBB:41:1:041

Source DB:  PubMed          Journal:  Cell Biochem Biophys        ISSN: 1085-9195            Impact factor:   2.194


  4 in total

1.  Fractal analysis and ionic dependence of endocytotic membrane activity of human breast cancer cells.

Authors:  Monika Krasowska; Zbigniew J Grzywna; Maria E Mycielska; Mustafa B A Djamgoz
Journal:  Eur Biophys J       Date:  2009-07-18       Impact factor: 1.733

2.  Mitochondrial-encoded membrane protein transcripts are pyrimidine-rich while soluble protein transcripts and ribosomal RNA are purine-rich.

Authors:  Patrick C Bradshaw; Anand Rathi; David C Samuels
Journal:  BMC Genomics       Date:  2005-09-26       Impact factor: 3.969

3.  Biocomplexity and Fractality in the Search of Biomarkers of Aging and Pathology: Focus on Mitochondrial DNA and Alzheimer's Disease.

Authors:  Annamaria Zaia; Pierluigi Maponi; Giuseppina Di Stefano; Tiziana Casoli
Journal:  Aging Dis       Date:  2017-02-01       Impact factor: 6.745

4.  Biocomplexity and Fractality in the Search of Biomarkers of Aging and Pathology: Mitochondrial DNA Profiling of Parkinson's Disease.

Authors:  Annamaria Zaia; Pierluigi Maponi; Martina Zannotti; Tiziana Casoli
Journal:  Int J Mol Sci       Date:  2020-03-04       Impact factor: 5.923

  4 in total

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