Primary structure of the murine adenovirus type 1 proteinase.

The DNA sequence of an open reading frame (ORF) corresponding to the murine adenovirus type 1 (Mav1) proteinase gene was determined. 1162 base pairs were sequenced from the downstream end of the SmaI-D Mav1 genomic fragment. The sequence defines the 204 amino acid proteinase, which apparently does not possess the usual L3 polyadenylation signal, but instead the sequence AAATAA. This gene is followed by a 147 amino acid C-terminal portion of the DNA-binding protein, encoded by the complementary strand.