Literature DB >> 15368749

The nature and significance of behavioural genetic information.

Ainsley Newson1.   

Abstract

In light of the human genome project, establishing the genetic aetiology of complex human diseases has become a research priority within Western medicine. However, in addition to the identification of disease genes, numerous research projects are also being undertaken to identify genes contributing to the development of human behavioural characteristics, such as cognitive ability and criminal tendency. The permissibility of this research is obviously controversial: will society benefit from this research, or will it adversely affect our conceptions of ourselves and each other? When assessing the permissibility of this research, it is important to consider the nature and deterministic significance of behavioural genetic information. Whilst to date there has been much discussion and debate about the properties of genetic information per se and genetic determinism, this has not been applied to behavioural genetic research and its ethical implications. Therefore, this paper elucidates how behavioural genetic information can be distinguished from other types of genetic and non-genetic information and also synthesizes the determinative significance of genetic factors for the development of human behavioural traits. Undertaking this analysis enables the ethical issues raised by this research to be debated in an appropriate context and indicates that separate policy considerations are warranted.

Entities:  

Keywords:  Biomedical and Behavioral Research; Genetics and Reproduction

Mesh:

Year:  2004        PMID: 15368749     DOI: 10.1023/b:meta.0000033764.50604.85

Source DB:  PubMed          Journal:  Theor Med Bioeth        ISSN: 1386-7415


  26 in total

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Authors:  L O Gostin; J G Hodge
Journal:  Jurimetrics       Date:  1999

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Journal:  Zygon       Date:  1997-03

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Authors:  K Bayertz
Journal:  J Med Philos       Date:  1998-06

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Journal:  Br J Psychiatry       Date:  1997-09       Impact factor: 9.319

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Journal:  Science       Date:  1997-06-06       Impact factor: 47.728

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Authors:  T Fogle
Journal:  Perspect Biol Med       Date:  1995       Impact factor: 1.416

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Authors:  J Maddox
Journal:  Nature       Date:  1984 Jun 14-20       Impact factor: 49.962

8.  The question not asked: the challenge of pleiotropic genetic tests.

Authors:  Robert Wachbroit
Journal:  Kennedy Inst Ethics J       Date:  1998-06

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Authors:  R Plomin; G E McClearn; D L Smith; S Vignetti; M J Chorney; K Chorney; C P Venditti; S Kasarda; L A Thompson; D K Detterman
Journal:  Behav Genet       Date:  1994-03       Impact factor: 2.805

Review 10.  Genetic fatalism and social policy: the implications of behavior genetics research.

Authors:  J S Alper; J Beckwith
Journal:  Yale J Biol Med       Date:  1993 Nov-Dec
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  1 in total

1.  Substance use disorder genetic research: investigators and participants grapple with the ethical issues.

Authors:  Marilyn E Coors; Kristen M Raymond
Journal:  Psychiatr Genet       Date:  2009-04       Impact factor: 2.458

  1 in total

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