Literature DB >> 15368690

The impact of prostatectomy and brachytherapy in patients with localized prostate cancer.

Felipe Reis1, Nelson Rodrigues Netto, José Alberto S Reinato, Marcelo Thiel, Emerson Zani.   

Abstract

PURPOSE: to compare urinary incontinence and erectile dysfunction symptoms reflecting quality of life and the willingness to undergo treatment again in patients treated by radical retropubic prostatectomy and low dose radiation (LDR) brachytherapy.
MATERIALS AND METHODS: from July 1992 to November 2001, 158 patients with clinical localized prostate cancer were treated by radical retropubic prostatectomy with or without nerve sparring or LDR brachytherapy. To all the 158 patients we mailed a self-reporting questionnaire with 5 questions to access sexual function, 4 questions for urinary continence, and 2 for the satisfaction with the treatment and willingness to undergo treatment again. Patients had no form of adjuvant radiation therapy, or neoadjuvant or adjuvant androgen suppression therapy. A total of 56 patients (43%), 34 of the prostatectomy and 22 patients of the brachytherapy group answered the questionnaire. Questionnaire results were independently analyzed by someone else not involved with patients' treatment.
RESULTS: patients self-reported some degree of erectile dysfunction in 84.8% (p = 0.01) in the group treated by prostatectomy and 23.07% (p = 0.86) in the brachytherapy group. Urinary incontinence occurred in 17.6% in the group treated by prostatectomy (p = 0.01) and in 9.5% (p = 0.52) in the brachytherapy group. Urinary incontinence and impotence significantly affected treatment satisfaction. However, considering satisfaction with the treatment and willingness to undergo treatment again, 88.2% of patients would elect surgery again and 95.5% brachytherapy again.

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Mesh:

Year:  2004        PMID: 15368690     DOI: 10.1023/b:urol.0000034686.55747.a5

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN: 0301-1623            Impact factor:   2.370


  14 in total

1.  The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction.

Authors:  R C Rosen; A Riley; G Wagner; I H Osterloh; J Kirkpatrick; A Mishra
Journal:  Urology       Date:  1997-06       Impact factor: 2.649

2.  Multicenter patient self-reporting questionnaire on impotence, incontinence and stricture after radical prostatectomy.

Authors:  T C Kao; D F Cruess; D Garner; J Foley; T Seay; P Friedrichs; J B Thrasher; R D Mooneyhan; D G McLeod; J W Moul
Journal:  J Urol       Date:  2000-03       Impact factor: 7.450

3.  Effects of psychosocial interventions with adult cancer patients: a meta-analysis of randomized experiments.

Authors:  T J Meyer; M M Mark
Journal:  Health Psychol       Date:  1995-03       Impact factor: 4.267

4.  Quality-of-life comparison of radical prostatectomy and interstitial brachytherapy in the treatment of clinically localized prostate cancer.

Authors:  T Krupski; G R Petroni; E A Bissonette; D Theodorescu
Journal:  Urology       Date:  2000-05       Impact factor: 2.649

5.  Quality-of-life outcomes for men with prostate carcinoma detected by screening.

Authors:  D S Smith; G F Carvalhal; K Schneider; J Krygiel; Y Yan; W J Catalona
Journal:  Cancer       Date:  2000-03-15       Impact factor: 6.860

6.  Prostate brachytherapy: treatment strategies.

Authors:  N N Stone; R G Stock
Journal:  J Urol       Date:  1999-08       Impact factor: 7.450

7.  Quality of life: radical prostatectomy versus radiation therapy for prostate cancer.

Authors:  A J Lim; A H Brandon; J Fiedler; A L Brickman; C I Boyer; W A Raub; M S Soloway
Journal:  J Urol       Date:  1995-10       Impact factor: 7.450

8.  Older patients' willingness to trade off urologic adverse outcomes for a better chance at five-year survival in the clinical setting of prostate cancer.

Authors:  D J Mazur; J F Merz
Journal:  J Am Geriatr Soc       Date:  1995-09       Impact factor: 5.562

9.  Quality-of-life outcomes in men treated for localized prostate cancer.

Authors:  M S Litwin; R D Hays; A Fink; P A Ganz; B Leake; G E Leach; R H Brook
Journal:  JAMA       Date:  1995-01-11       Impact factor: 56.272

10.  Cancer control and quality of life following anatomical radical retropubic prostatectomy: results at 10 years.

Authors:  P C Walsh; A W Partin; J I Epstein
Journal:  J Urol       Date:  1994-11       Impact factor: 7.450

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