Literature DB >> 15367501

Biochemical markers of myocyte injury in heart failure.

Y Sato1, T Kita, Y Takatsu, T Kimura.   

Abstract

This review discusses the role of biochemical markers of myocyte injury in patients with chronic congestive heart failure. Heart specific assays have been developed for the measurement of cardiac troponin T (cTnT), cardiac troponin I (cTnI), heart type fatty acid binding protein (H-FABP), and myosin light chain 1 (MLC-1). Concentrations of these biochemical markers increase in the absence of ischaemic events in the subset of patients with heart failure whose long term outcomes are most adverse. The markers are easy to measure serially and it is therefore easy to follow patients without inter-observer variability. The serial clinical use of these markers, separately or in combination, will sharpen our understanding of the state of heart failure.

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Year:  2004        PMID： 15367501      PMCID： PMC1768497          DOI： 10.1136/hrt.2003.023895

Source DB:  PubMed          Journal:  Heart        ISSN： 1355-6037            Impact factor:   5.994


  48 in total

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Review 3.  Left ventricular remodeling after myocardial infarction: pathophysiology and therapy.

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5.  Clinical significance of elevated levels of cardiac troponin T in patients with chronic heart failure.

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Journal:  Am J Cardiol       Date:  1999-09-01       Impact factor: 2.778

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Authors: 
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Journal:  Am Heart J       Date:  1998-10       Impact factor: 4.749
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  20 in total

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7.  A case of critical aortic stenosis masquerading as acute coronary syndrome.

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8.  Cardiac troponin I as prognostic marker in heart failure patients discharged from emergency department.

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Journal:  Intern Emerg Med       Date:  2008-02-14       Impact factor: 3.397

9.  Detection of differentially methylated gene promoters in failing and nonfailing human left ventricle myocardium using computation analysis.

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10.  Histamine 2 receptor antagonism elicits protection against doxorubicin-induced cardiotoxicity in rodent model.

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Journal:  Mol Cell Biochem       Date:  2017-09-08       Impact factor: 3.396
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